ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2009
Imaging of desmoplastic infantile ganglioglioma: a spectroscopic viewpoint.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 15 citations in OpenAlex.
- Radiohistogenomics of pediatric low-grade neuroepithelial tumors.Neuroradiology · 2021Review
- Non-infantile variant of desmoplastic ganglioglioma: Conventional and advanced MR imaging characteristics.The neuroradiology journal · 2015Article
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Authors and funding
2 authors at 1 institution in 2 countries.
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Abstract
purposeDesmoplastic infantile gangliogliomas (DIG) are rare benign intracranial neoplasms of early childhood with involvement of superficial cerebral cortex and leptomeninges. The purpose of the study was to determine the alterations in metabolite ratios occurring in the neoplasm and combine with magnetic resonance (MR) imaging features to narrow down the diagnosis.
methodsMR imaging sequences include T1- and T2-weighted sequences, fluid-attenuated inversion recovery sequences, and post-gadolinium-contrast T1-weighted imaging. Single-voxel short TE (1)H MR spectroscopy was used to study the changes in metabolite ratios in the tumor.
resultsComparison of metabolite ratios between normal brain tissue and tumor-affected region showed lower N-acetyl aspartate to creatine (Cr; 1.58 vs.1.28), higher choline to Cr (0.82 vs.2.03), and no significant change in myo-inositol to Cr (0.42 vs.0.39).
conclusionMR spectroscopy and imaging provide valuable information in the diagnosis of DIG.
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