ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2009
Pathophysiological mechanism of ipsilateral cerebral and brainstem hemiatrophy in basal ganglia germ cell tumors: case report.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Germinoma of basal ganglia.Radiology case reports · 2024Article
- [Clinical analysis of 30 cases of basal ganglia germinoma in children].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022Article
- Ectopic Germinoma: A Delayed Diagnosis With Serial Magnetic Resonance Imaging Features.Cureus · 2021Article
- Clinico-radiological approach to cerebral hemiatrophy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Review
- Clinical features, radiologic findings, and treatment of pediatric germ cell tumors involving the basal ganglia and thalamus: a retrospective series of 15 cases at a single center.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- Early imaging findings in germ cell tumors arising from the basal ganglia.Pediatric radiology · 2016Article
- Progressive hemiparesis in a young man: Hemicerebral atrophy as the initial manifestation of basal ganglia germinoma.Asian journal of neurosurgeryArticle
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3 authors at 1 institution in 1 country.
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Abstract
introductionThe basal ganglia is an uncommon location for germ cell tumors. It has been reported that basal ganglia germinomas and mixed germ cell tumors are associated with ipsilateral cerebral and brainstem hemiatrophy on presentation. Several pathophysiological mechanisms including autoimmune process and direct tumor infiltration of the thalamus or the internal capsule have been postulated to explain this association. CASE REPORTS: The authors report two boys, aged 7 and 10, with basal ganglia germ cell tumors. Both of them presented with gradual onset of hemiparesis and had features of ipsilateral cerebral and brainstem hemiatrophy on imaging studies. They underwent chemotherapy followed by reduced dose radiotherapy with good response. DISCUSSION: Pathophysiological mechanisms of the associated ipsilateral cerebral and brainstem hemiatrophy are discussed. The authors postulate that the gradual obliteration of the perforating arteries to the diencephalon especially the lenticulostriate arteries of the prebifurcation middle cerebral artery may be the major mechanism of the associated hemiatrophy.
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