Evidence map›Paper›PMID 19139804›Full record

ReviewThe journal of headache and pain2009

Cardiac cephalgia.

Annamaria Bini, Andrea Evangelista, Paola Castellini, Giorgio Lambru, Tullia Ferrante, Gian Camillo Manzoni, Paola Torelli

Abstract readReview
In one paragraph

Review in The journal of headache and pain, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Ischaemic Heart Disease Masquerading as Headache: A Case Series.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
  7. Review
  8. Article
  9. Headache and sick sinus syndrome: A case report.World journal of clinical cases · 2020
    Article
  10. Article
  11. Headaches of the elderly.Current neurology and neuroscience reports · 2015
    Review
  12. Cardiac cephalgia: A headache of the heart.Journal of cardiology cases · 2015
    Article
  13. Article
  14. Cardiac cephalgia.Current pain and headache reports · 2015
    Review
  15. Cardiac Cephalgia.Cardiology research · 2014
    Article
  16. Tension-type headache and systemic medical disorders.Current pain and headache reports · 2011
    Review
  17. Diagnosis of acute headache.Current pain and headache reports · 2011
    Article
  18. Cardiac cephalalgia: First case from India.Annals of Indian Academy of Neurology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Annamaria BiniDepartment of Neuroscience, Headache Centre, University of Parma, Parma, Italy. bini.annamaria@alice.it
Andrea Evangelista
Paola Castellini
Giorgio Lambru
Tullia Ferrante
Gian Camillo Manzoni
Paola Torelli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this review was to provide a critical evaluation of medical literature on so-called "cardiac cephalgia" or "cardiac cephalalgia". The 2004 International Classification of Headache Disorders codes cardiac cephalgia to 10.6 in the group of secondary headaches attributed to disorder of homoeostasis. This headache is hardly recognizable and is associated to an ischaemic cardiovascular event, of which it may be the only manifestation in 27% of cases. It usually occurs after exertion. Sometimes routine examinations, cardiac enzymes, ECG and even exercise stress test prove negative. In such cases, only a coronary angiogram can provide sufficient evidence for diagnosis. Cardiac cephalgia manifests itself without a specific pattern of clinical features: indeed, in this headache subtype there is a high variability of clinical manifestations between different patients and also within the same patient. It "mimics" sometimes a form of migraine either accompanied or not by autonomic symptoms, sometimes a form of tension-type headache; on other occasions, it exhibits characteristics that can hardly be interpreted as typical of primary headache. Pain location is highly variable. When the headache occurs as the only manifestation of an acute coronary event, the clues for suspicion are a) older age at onset, b) no past medical history of headache, c) presence of risk factors for vascular disorders and d) onset of headache under stress. Knowledge of cardiac cephalgia is scarce, due to its rare clinical occurrence and to the scant importance given to headache as a symptom concomitantly with an ischaemic cardiac event.

Indexed as

Coronary AngiographyDiagnosis, DifferentialElectrocardiographyElectroencephalographyHeadache Disorders, SecondaryHumansMigraine DisordersMyocardial IschemiaTension-Type Headache

Identifiers

PMID19139804
PMCPMC3451760

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.