ArticleMalaria journal2009
Prevalence of Plasmodium spp. in malaria asymptomatic African migrants assessed by nucleic acid sequence based amplification.
Article in Malaria journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05086887 (Infections in Migrants in Sweden - the Importance of Malaria and Other Parasitic Infections), which is not on this map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Infections in Migrants in Sweden - the Importance of Malaria and Other Parasitic Infections
Who cites it
26 citing papers in PubMed, 57 citations in OpenAlex.
- Burden of asymptomatic malaria in adult sub-Saharan migrants attending an outpatient clinic in Rome from February 2024 to January 2025.Infectious diseases of poverty · 2025Article
- Clinical Findings in Migrants With AsymptomaticOpen forum infectious diseases · 2025Article
- Article
- Malaria parasite prevalence in Sub-Saharan African migrants screened in Sweden: a cross-sectional study.The Lancet regional health. Europe · 2023Article
- Malaria Falciparum: Relapse After a Decade.Cureus · 2022Article
- Current methods for the detection ofCurrent research in parasitology & vector-borne diseases · 2022Review
- Dissecting disease tolerance in Plasmodium vivax malaria using the systemic degree of inflammatory perturbation.PLoS neglected tropical diseases · 2021Article
- Plasmodium-a brief introduction to the parasites causing human malaria and their basic biology.Journal of physiological anthropology · 2021Review
- Study of the diagnostic accuracy of microbiological techniques in the diagnosis of malaria in the immigrant population in Madrid.Malaria journal · 2018Article
- Fatal Postoperative Hemolysis Due to Severe Falciparum Malaria.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2017Article
- Assessment of submicroscopic infections and gametocyte carriage of Plasmodium falciparum during peak malaria transmission season in a community-based cross-sectional survey in western Kenya, 2012.Malaria journal · 2016Article
- A paper and plastic device for the combined isothermal amplification and lateral flow detection of Plasmodium DNA.Malaria journal · 2015Article
- The duration of Plasmodium falciparum infections.Malaria journal · 2014Review
- Chronic malaria revealed by a new fluorescence pattern on the antinuclear autoantibodies test.PloS one · 2014Article
- Management of imported malaria in Europe.Malaria journal · 2012Review
- Emerging nucleic acid-based tests for point-of-care detection of malaria.The American journal of tropical medicine and hygiene · 2012Review
- Migration and malaria in europe.Mediterranean journal of hematology and infectious diseases · 2012Article
- Evidence-based clinical guidelines for immigrants and refugees.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2011Article
- Cytochrome b gene quantitative PCR for diagnosing Plasmodium falciparum infection in travelers.Journal of clinical microbiology · 2011Article
- Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination.Clinical microbiology reviews · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalaria is one of the most important infectious diseases in the world. Although most cases are found distributed in the tropical regions of Africa, Asia, Central and South Americas, there is in Europe a significant increase in the number of imported cases in non-endemic countries, in particular due to the higher mobility in today's society.
methodsThe prevalence of a possible asymptomatic infection with Plasmodium species was assessed using Nucleic Acid Sequence Based Amplification (NASBA) assays on clinical samples collected from 195 study cases with no clinical signs related to malaria and coming from sub-Saharan African regions to Southern Italy. In addition, base-line demographic, clinical and socio-economic information was collected from study participants who also underwent a full clinical examination.
resultsSixty-two study subjects (31.8%) were found positive for Plasmodium using a pan Plasmodium specific NASBA which can detect all four Plasmodium species causing human disease, based on the small subunit 18S rRNA gene (18S NASBA). Twenty-four samples (38%) of the 62 18S NASBA positive study cases were found positive with a Pfs25 mRNA NASBA, which is specific for the detection of gametocytes of Plasmodium falciparum. A statistically significant association was observed between 18S NASBA positivity and splenomegaly, hepatomegaly and leukopaenia and country of origin.
conclusionThis study showed that a substantial proportion of people originating from malaria endemic countries harbor malaria parasites in their blood. If transmission conditions are available, they could potentially be a reservoir. Therefore, health authorities should pay special attention to the health of this potential risk group and aim to improve their health conditions.
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Registered trials
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