Evidence map›Paper›PMID 19137353›Full record

Trial reportClinical rheumatology2009

Comparison of therapeutic effects of sodium hyaluronate and corticosteroid injections on trapeziometacarpal joint osteoarthritis.

Cengiz Bahadir, Burcu Onal, Vildan Yaman Dayan, Nuriye Gürer

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical rheumatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03089723 (Comparative Study of the Intraarticular Treatment of Carpometacarpal Joint Ostearthritis of the Thumb With Lavage With Saline Solution, or Lavage and Injection of Hyaluronic Acid and Mannitol.), which is not on this map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03089723 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Comparative Study of the Intraarticular Treatment of Carpometacarpal Joint Ostearthritis of the Thumb With Lavage With Saline Solution, or Lavage and Injection of Hyaluronic Acid and Mannitol.

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2017 to 2019Enrolled40ConditionsRhizarthrosis, Metabolic DiseaseArmsVisual Analog Scale (VAS), Range of Motion (ROM), Palmar grip strength, Lateral grip strength, Pulp-pulp pinch strength
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 91 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Cengiz BahadirPhysical Medicine and Rehabilitation Clinic, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey, cengizmd@gmail.com.
Burcu Onal
Vildan Yaman Dayan
Nuriye Gürer
Haydarpaşa Numune Eğitim ve Araştırma Hastanesi · TRAcıbadem Kadıköy Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This was a randomized, open-label, evaluator-blinded clinical study including 40 women with stage II or III trapeziometacarpal joint osteoarthritis. The steroid group (n = 20) received one injection of 20 mg triamcinolone acetonide once and the hyaluronate group (n = 20) received three injections of 5 mg sodium hyaluronate at 1-week intervals. The pain level was assessed using a visual analog scale and grip and pinch strengths were measured using a hand grip dynomemeter and pinch gauge. The Duruöz Hand Index was used to evaluate hand function. Pain level decreased significantly over 12 months for the steroid group and over 6 months for the sodium hyaluronate group. Pinch strength did not improve in either group, but grip strength improved significantly in both groups. Hand function improved in both groups but it was only significant in the steroid group. Our findings showed that both intra-articular injection of steroid and sodium hyalurunate are effective in trapeziometacarpal joint osteoarthritis. However the steroid injection was found to be superior to sodium hyaluronate injection in reducing pain and improving hand function.

Indexed as

Adjuvants, ImmunologicAdrenal Cortex HormonesAgedAged, 80 and overCarpometacarpal JointsFemaleHand StrengthHumansHyaluronic AcidInjections, Intra-ArticularJoint DiseasesMiddle AgedOsteoarthritisPain MeasurementSingle-Blind MethodSteroidsAdjuvants, ImmunologicAdrenal Cortex HormonesHyaluronic AcidSteroids

Identifiers

PMID19137353
OpenAlexW2054928713

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.