ReviewClinical oral investigations2009
The oral cavity--a key system to understand substratum-dependent bioadhesion on solid surfaces in man.
Review in Clinical oral investigations, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
91 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Preventive and Therapeutic Effects of Plant-Derived Compounds on Tooth Erosion: A Systematic Review and Meta-Analysis of In Situ and In Vitro Studies.Clinical and experimental dental research · 2025Pooled it
- In situ antimicrobial activity on oral biofilm: essential oils vs. 0.2 % chlorhexidine.Clinical oral investigations · 2015Trial
- Do edible oils reduce bacterial colonization of enamel in situ?Clinical oral investigations · 2013Trial
- Article
- Surface-related factors affecting bacterial adhesion on dental implants: a short literature review.The journal of advanced prosthodontics · 2026Review
- The Effect of Toothpaste Suspensions on the Formation of Oral Biofilms In Situ.International dental journal · 2026Article
- Surface Properties of Dental Materials Influence the In Vitro Multi-Species Biofilm Formation.Polymers · 2026Article
- Acrylic-based occlusal device materials - the influence of manufacturing techniques on material properties and the propensity for biofilm formation.Biomaterial investigations in dentistry · 2026Article
- Clinical and Microbiological Effects of Smoking on Lithium Disilicate Endocrowns: An Age-Stratified Cross-Sectional Study.Dentistry journal · 2026Article
- Synthetic hydroxyapatite: a perfect substitute for dental enamel in biofilm formation studies.Scientific reports · 2025Article
- Targeting the Oral Mucosa: Emerging Drug Delivery Platforms and the Therapeutic Potential of Glycosaminoglycans.Pharmaceutics · 2025Review
- Evaluation of early bacterial adhesion on CAD/CAM dental materials: an in situ study.Odontology · 2025Article
- Exploration of the primary antibiofilm substance and mechanism employed byFrontiers in cellular and infection microbiology · 2025Article
- Effects ofFoods (Basel, Switzerland) · 2024Article
- The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review.Dentistry journal · 2024Review
- The effect of dental material type and masticatory forces on periodontitis-derived subgingival microbiomes.Biofilm · 2024Article
- The Contribution of Scanning Force Microscopy on Dental Research: A Narrative Review.Materials (Basel, Switzerland) · 2024Review
- Article
- Optimizing the use of low-frequency ultrasound for bacterial detachment of in vivo biofilms in dental research-a methodological study.Clinical oral investigations · 2023Article
- Ex vivo study of molecular changes of stained teeth following hydrogen peroxide and peroxymonosulfate treatments.Scientific reports · 2023Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the greatest challenges in life sciences and biomaterials research is adhesion of biomolecules and bacteria to solid surfaces in aqueous solutions. An example concerning everybody is biofilm formation in the oral cavity on dental materials and dental hard substances, respectively. The main characteristics typical for any bioadhesion can be observed excellently in the oral cavity. Initially, a proteinaceous layer termed pellicle is formed. It mediates the interactions between solid substrata, oral fluids and microorganisms. Numerous different materials with differing physico-chemical properties and possible impact on the acquired pellicle are present in the oral cavity such as enamel, dentine, restorative materials or dental implants. Despite the fact that in vitro studies demonstrate considerable differences of experimental pellicles formed on these materials, the in situ pellicles seem to be relatively similar and level off the different properties of the underlying substrates. However, the bacterial colonisation of pellicle-coated surfaces under in vivo conditions differs considerably. Long-range forces and detachment of biofilm layers may account for this phenomenon despite the masking effect of the pellicle. Accordingly, low-energy surfaces are desirable for restorative materials exposed to the oral cavity to minimise bacterial adhesion. The oral cavity is an easy accessible in vivo model for understanding bioadhesion and for investigation of protein-surface interactions noninvasively. For evaluation of biofilm formation on dental materials, in situ or in vivo studies are preferable.
Indexed as
Identifiers
19137331What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.