Evidence map›Paper›PMID 19136143›Full record

ReviewSeminars in arthritis and rheumatism2010

Understanding the epidemiology and progression of systemic lupus erythematosus.

Guillermo J Pons-Estel, Graciela S Alarcón, Lacie Scofield, Leslie Reinlib, Glinda S Cooper

4 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Seminars in arthritis and rheumatism, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 351 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
351citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03426384 nacompletednot on this mapstarted 2018, after this paper: background citation

Can Individualized Diet and Lifestyle Modifications Derived From Digital Therapeutics and Health Coaching Improve Symptoms of Systemic Lupus Erythematosus

TypeinterventionalSponsorMymee Inc.Ran2018 to 2019Enrolled50ConditionsSystem, Lupus ErythematosusArmsMymee Program
NCT05516511 unknown statusnot on this mapstarted 2023, after this paper: background citation

Serum Levels of Angiotensin Converting Enzyme in Systemic Lupus Erythematous Patients

TypeobservationalSponsorSohag UniversityRan2023 to 2023Enrolled75ConditionsSystemic Lupus ErythematosusArmsAngiotensin Converting Enzyme test
NCT05964751 unknown statusnot on this mapstarted 2023, after this paper: background citation

the Association Between Metabolic Syndrome and Its Components With Lupus Nephritis in Systemic Lupus Erythematosus Patients

TypeobservationalSponsorSohag UniversityRan2023 to 2024Enrolled120ConditionsLupus NephritisArmslipid profile, fasting blood suger
NCT06119763 unknown statusnot on this mapstarted 2023, after this paper: background citation

Anti-DFS70 Antibodies and it's Relationship With Systemic Lupus Erythematosus Manifestations

TypeobservationalSponsorSohag UniversityRan2023 to 2024Enrolled50ConditionsSystemic Lupus ErythematosusArmsanti dfs70 antibodies
3 · Its place in the literature

Who cites it

351 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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291 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Guillermo J Pons-EstelDivision of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Graciela S Alarcón
Lacie Scofield
Leslie Reinlib
Glinda S Cooper

Funding

Intramural NIH HHS Z99 ES999999
6 · The paper itself

Abstract

objectivesThis review examines the burden and patterns of disease in systemic lupus erythematosus (SLE) and the influence and interactions of gender, ethnicity, age, and psychosocial attributes with respect to disease progression, focusing on issues relevant to clinical practice and research.

methodsPubMed literature search complemented by review of bibliographies listed in identified articles.

resultsAn increased risk among reproductive age women is clearly seen in African Americans in the United States. However, in other populations, a different pattern is generally seen, with the highest age-specific incidence rates occurring in women after age 40 years. The disease is 2 to 4 times more frequent, and more severe, among nonwhite populations around the world and tends to be more severe in men and in pediatric and late-onset lupus. SLE patients now experience a higher than 90% survival rate at 5 years. The less favorable survival experience of ethnic minorities is possibly related to socioeconomic status rather than to ethnicity per se, and adequate social support has been shown to be a protective factor, in general, in SLE patients. Discordance between physician and patient ratings of disease activity may affect quality of care.

conclusionsOur understanding of ways to improve outcomes in SLE patients could benefit from patient-oriented research focusing on many dimensions of disease burden. Promising research initiatives include the inclusion of community-based patients in longitudinal studies, use of self-assessment tools for rating disease damage and activity, and a focus on self-perceived disease activity and treatment compliance.

Indexed as

Disease ProgressionAge FactorsAge of OnsetBlack or African AmericanFemaleHumansIncidenceLupus Erythematosus, SystemicMalePrevalenceSex FactorsUnited States

Identifiers

PMID19136143
PMCPMC2813992

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.