Evidence map›Paper›PMID 19136134›Full record

ReviewVirology2009

Small DNA tumor viruses: large contributors to biomedical sciences.

Peter M Howley, David M Livingston

Abstract readReview
In one paragraph

Review in Virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The adenovirus DNA-binding protein DBP.Journal of virology · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Small size, big impact: how studies of small DNA tumour viruses revolutionized biology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
  13. Review
  14. Article
  15. Article
  16. Molecular mechanisms of viral oncogenesis in humans.Nature reviews. Microbiology · 2018
    Review
  17. Review
  18. Review
  19. Take your PIKK: tumour viruses and DNA damage response pathways.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter M HowleyDepartment of Pathology, Harvard Medical School, Boston, MA 02115, USA. peter_howley@hms.harvard.edu
David M Livingston

Funding

VIRAL ONCOPROTEIN PERTURBATION OF RB/E2F PATHWAYP01CA050661 · NCI · DANA-FARBER CANCER INSTITUTE · PI HOWLEY, PETER M · 1989 to 2013
$35.8M
NCI NIH HHS P01 CA050661
6 · The paper itself

Abstract

Studies of the small DNA tumor viruses (the polyomaviruses, the adenoviruses and the papillomaviruses) have led to fundamental discoveries that have advanced our understanding of basic mammalian cell molecular biology processes such as transcription and DNA replication, uncovered pathways and genes often perturbed in human cancer, and identified bona fide human cancer viruses. In this article we examine the many contributions that have come from the small DNA tumor virus field and provide a recounting of some of the major landmark discoveries.

Indexed as

AdenoviridaeCell Transformation, ViralDNA ReplicationDNA Tumor VirusesHumansNeoplasmsPapillomaviridaePolyomavirus

Identifiers

PMID19136134
PMCPMC2662339

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.