ArticleBMC evolutionary biology2009
Sleeping to fuel the immune system: mammalian sleep and resistance to parasites.
Article in BMC evolutionary biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Article
- IL-1b and TNF-a-driven sleep alterations: Neuroimmune mechanisms and behavioral implications.Brain, behavior, & immunity - health · 2025Review
- Associations between subjective sleep quality and inflammatory markers in patients with treatment-resistant depression.CNS spectrums · 2025Article
- Naps, night-time sleep and cognitive function among middle-aged and older people in China.PloS one · 2025Article
- The impact of entertainment screen time on sleep quality in Chinese and British adolescents: a moderated mediation model.Frontiers in psychology · 2025Article
- Shifted levels of sleep and activity during the night as mechanisms underlying ectoparasite resistance.Npj biological timing and sleep · 2025Article
- Self-control and bed procrastination as mediators between mindfulness and sleep quality among college students during the COVID-19 pandemic.Scientific reports · 2024Article
- Factors associated with survival after early at-home NIV initiation in ALS patients.Journal of neurology · 2024Article
- Review
- Physical activity and sleep relate to antibody maintenance following naturalistic infection and/or vaccination in older adults.Brain, behavior, & immunity - health · 2023Article
- Sleep and Neuroimmunomodulation for Maintenance of Optimum Brain Function: Role of Noradrenaline.Brain sciences · 2022Review
- Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster.PLoS pathogens · 2022Article
- Differential Effect of Light and Dark Period Sleep Fragmentation on Composition of Gut Microbiome and Inflammation in Mice.Life (Basel, Switzerland) · 2021Article
- Role of sleep deprivation in immune-related disease risk and outcomes.Communications biology · 2021Review
- Review
- Pervasive effects ofBiology letters · 2021Article
- Sleep Disturbance during Infection Compromises Tfh Differentiation and Impacts Host Immunity.iScience · 2020Article
- Article
- Relevance of deprivation studies in understanding rapid eye movement sleep.Nature and science of sleep · 2018Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Sleep is an enigma. Why animals forgo eating and reproducing, while potentially increasing their risk of predation remains unknown. Although some may question whether all animals sleep, it is clear that all living organisms possess defenses against attack by pathogens. Immune responses of humans and animals are impaired by sleep loss, and responses to immune challenge include altered sleep. Thus, sleep is hypothesized to be a component of the acute phase response to infection and to function in host defense. Examining phylogenetic relationships among sleep parameters, components of the mammalian immune system and resistance to infection may provide insight into the evolution of sleep and lead to a greater appreciation for the role of sleep in host defense.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.