Evidence map›Paper›PMID 19134122›Full record

ReviewCellular microbiology2009

Live cell fluorescence microscopy to study microbial pathogenesis.

Adam D Hoppe, Stephanie Seveau, Joel A Swanson

Open access · greenAbstract readReview
In one paragraph

Review in Cellular microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Contribution of high-content imaging technologies to the development of anti-infective drugs.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2016
    Review
  7. Article
  8. Deep-red fluorescent imaging probe for bacteria.Bioorganic & medicinal chemistry letters · 2012
    Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Adam D HoppeDepartment of Chemistry and Biochemistry, South Dakota State University, Brookings, SD 57007-0896, USA. adam.hoppe@sdstate.edu
Stephanie Seveau
Joel A Swanson
South Dakota State University · USUniversity of Michigan–Ann Arbor · US

Funding

Cellular Biotechnology Training Program (CBTP) - Years 31-35T32GM145304 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Guizhi Zhu · 2022 to 2026
$2.6M
MANIPULATION OF PHAGOCYTOSIS IN MACROPHAGESR01AI035950 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SWANSON, JOEL A · 1994 to 2008
$2.2M
Coordination of signaling during phagocytosisR01AI064668 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SWANSON, JOEL A · 2005 to 2010
$1.6M
MANIPULATION OF PHAGOCYTOSIS IN MACROPHAGESR21AI035950 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SWANSON, JOEL A · 1999 to 1999
–
NIAID NIH HHS AI-035950NIAID NIH HHS AI-064668NIAID NIH HHS R01 AI035950NIAID NIH HHS R01 AI064668NIAID NIH HHS R21 AI035950NIGMS NIH HHS T32 GM145304
6 · The paper itself

Abstract

Advances in microscopy and fluorescent probes provide new insight into the nanometer-scale biochemistry governing the interactions between eukaryotic cells and pathogens. When combined with mathematical modelling, these new technologies hold the promise of qualitative, quantitative and predictive descriptions of these pathways. Using the light microscope to study the spatial and temporal relationships between pathogens, host cells and their respective biochemical machinery requires an appreciation for how fluorescent probes and imaging devices function. This review summarizes how live cell fluorescence microscopy with common instruments can provide quantitative insight into the cellular and molecular functions of hosts and pathogens.

Indexed as

Host-Pathogen InteractionsAnimalsBacteriaBacterial InfectionsCells, CulturedEukaryotic CellsFluorescent DyesHumansMicroscopy, FluorescenceFluorescent Dyes

Identifiers

PMID19134122
PMCPMC2904246
OpenAlexW2150457818

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.