Trial reportDepression and anxiety2009
Pain interference impacts response to treatment for anxiety disorders.
Trial report in Depression and anxiety, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 51 citations in OpenAlex.
- Effects of pain and prescription opioid use on outcomes in a collaborative care intervention for anxiety.The Clinical journal of pain · 2013Trial
- Effects of eye movement desensitization and reprocessing (EMDR) on non-specific chronic back pain: a randomized controlled trial with additional exploration of the underlying mechanisms.BMC musculoskeletal disorders · 2013Trial
- Pain adversely affects outcomes to a collaborative care intervention for anxiety in primary care.Journal of general internal medicine · 2013Trial
- Prevention of Pain Interference in Insomnia Patients via Digital Cognitive-Behavioral Therapy for Insomnia.Behavioral sleep medicineTrial
- Anxiety and fear of cancer recurrence as predictors of subsequent pain interference in early cancer survivorship: Exploring the moderating roles of cognitive and emotional factors.Journal of behavioral medicine · 2024Article
- Longitudinal Associations of PROMIS-29 Anxiety and Depression Symptoms With Low Back Pain Impact in a Sample of U.S. Military Service Members.Military medicine · 2023Article
- Chronic pain and spinal cord stimulation.Medicine · 2020Observational
- Group differences in pain interference, psychiatric disorders, and general medical conditions among Hispanics and whites in the U.S. general population.Psychiatry research · 2017Article
- Alterations in opioid inhibition cause widespread nociception but do not affect anxiety-like behavior in oral cancer mice.Neuroscience · 2017Article
- Body Pain Intensity and Interference in Adults (45-53 Years Old): A Cross-Sectional Survey in Chongqing, China.International journal of environmental research and public health · 2016Article
- Pain, not chronic disease, is associated with the recurrence of depressive and anxiety disorders.BMC psychiatry · 2014Article
- Article
- Pain interference and incident mood, anxiety, and substance-use disorders: findings from a representative sample of men and women in the general population.Journal of psychiatric research · 2013Article
- Quality of life in panic disorder: looking beyond symptom remission.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2012Review
- Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain.Behavioural brain research · 2012Article
- Prevalence and psychiatric correlates of pain interference among men and women in the general population.Journal of psychiatric research · 2012Article
- Pain Interference, Psychopathology, and General Medical Conditions Among Black and White Adults in the US General Population.Journal of addiction medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAnxiety disorders and pain are commonly comorbid, though little is known about the effect of pain on the course and treatment of anxiety.
methodsThis is a secondary analysis of a randomized controlled trial for anxiety treatment in primary care. Participants with panic disorder (PD) and/or generalized anxiety disorder (GAD) (N=191; 81% female, mean age 44) were randomized to either their primary-care physician's usual care or a 12-month course of telephone-based collaborative care. Anxiety severity, pain interference, health-related quality of life, health services use, and employment status were assessed at baseline, and at 2-, 4-, 8-, and 12-month follow-up. We defined response to anxiety treatment as a 40% or greater improvement from baseline on anxiety severity scales at 12-month follow-up.
resultsThe 39% who reported high pain interference at baseline had more severe anxiety (mean SIGH-A score: 21.8 versus 18.0, P<.001), greater limitations in activities of daily living, and more work days missed in the previous month (5.8 versus 4.0 days, P=.01) than those with low pain interference. At 12-month follow-up, high pain interference was associated with a lower likelihood of responding to anxiety treatment (OR=.28; 95% CI=.12-.63) and higher health services use (26.1% with >/=1 hospitalization versus 12.0%, P<.001).
conclusionsPain that interferes with daily activities is prevalent among primary care patients with PD/GAD and associated with more severe anxiety, worse daily functioning, higher health services use, and a lower likelihood of responding to treatment for PD/GAD.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.