Evidence map›Paper›PMID 19133126›Full record

ArticleMicrobial cell factories2009

Learning about protein solubility from bacterial inclusion bodies.

Mónica Martínez-Alonso, Nuria González-Montalbán, Elena García-Fruitós, Antonio Villaverde

Abstract readEditorial
In one paragraph

Article in Microbial cell factories, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  9. A Novel Chimeric Endolysin with Antibacterial Activity against Methicillin-ResistantFrontiers in cellular and infection microbiology · 2017
    Article
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  19. Article
  20. Inclusion bodies: a new concept.Microbial cell factories · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mónica Martínez-AlonsoInstitute for Biotechnology and Biomedicine and Department of Genetics and Microbiology, Autonomous University of Barcelona, Barcelona, Spain. avillaverde@servet.uab.es.
Nuria González-Montalbán
Elena García-Fruitós
Antonio Villaverde

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The progressive solving of the conformation of aggregated proteins and the conceptual understanding of the biology of inclusion bodies in recombinant bacteria is providing exciting insights on protein folding and quality. Interestingly, newest data also show an unexpected functional and structural complexity of soluble recombinant protein species and picture the whole bacterial cell factory scenario as more intricate than formerly believed.

Identifiers

PMID19133126
PMCPMC2630952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.