ArticleMolecular genetics and genomics : MGG2009
Faithful inheritance of cytosine methylation patterns in repeated sequences of the allotetraploid tobacco correlates with the expression of DNA methyltransferase gene families from both parental genomes.
Article in Molecular genetics and genomics : MGG, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Stage-specific transcriptomic and DNA methylation responses to triploidy in European sea bass embryos and larvae.BMC genomics · 2025Article
- Regional active transcription associates with homoeologous exchange breakpoints in synthetic Brassica tetraploids.Plant physiology · 2024Article
- Biobanks in chronic disease management: A comprehensive review of strategies, challenges, and future directions.Heliyon · 2024Review
- The alternative transcription and expression characterization ofFrontiers in genetics · 2023Article
- Cross-kingdom transcriptomic trends in the evolution of hybrid gene expression.Journal of evolutionary biology · 2022Article
- Global Patterns of Subgenome Evolution in Organelle-Targeted Genes of Six Allotetraploid Angiosperms.Molecular biology and evolution · 2022Article
- Epigenetic variation: A major player in facilitating plant fitness under changing environmental conditions.Frontiers in cell and developmental biology · 2022Review
- DNA Methylation Silences Exogenous Gene Expression in Transgenic Birch Progeny.Frontiers in plant science · 2020Article
- Genetic and Epigenetic Changes Are Rapid Responses of the Genome to the Newly Synthesized AutotetraploidFrontiers in genetics · 2020Article
- Molecular characterization and transcription analysis of DNA methyltransferase genes in tomato (Solanum lycopersicum).Genetics and molecular biology · 2020Article
- Chromosomal distribution of H3K4me2, H3K9me2 and 5-methylcytosine: variations associated with polyploidy and hybridization in Brachiaria (Poaceae).Plant cell reports · 2016Article
- The origin of exon 3 skipping of paternal GLOBOSA pre-mRNA in some Nicotiana tabacum lines correlates with a point mutation of the very last nucleotide of the exon.Molecular genetics and genomics : MGG · 2016Article
- Timing of the G1/S transition in tobacco pollen vegetative cells as a primary step towards androgenesis in vitro.Plant cell reports · 2014Article
- Epigenetic switches of tobacco transgenes associate with transient redistribution of histone marks in callus culture.Epigenetics · 2013Article
- Three TERT genes in Nicotiana tabacum.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012Article
- Biotransformation of eugenol by suspension cultures of transgenic crown galls of Panax quinquefolium and suspension cultures of Nicotiana tabacum.World journal of microbiology & biotechnology · 2010Article
- Genome-wide patterns of homoeologous gene flow in allotetraploid coffee.Applications in plant sciencesArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The widespread occurrence of epigenetic alterations in allopolyploid species deserves scrutiny that DNA methylation systems may be perturbed by interspecies hybridization and polyploidization. Here we studied the genes involved in DNA methylation in Nicotiana tabacum (tobacco) allotetraploid containing S and T genomes inherited from Nicotiana sylvestris and Nicotiana tomentosiformis progenitors. To determine the inheritance of DNA methyltransferase genes and their expression patterns we examined three major DNA methyltransferase families (MET1, CMT3 and DRM) from tobacco and the progenitor species. Using Southern blot hybridization and PCR-based methods (genomic CAPS), we found that the parental loci of these gene families are retained in tobacco. Homoeologous expression was found in all tissues examined (leaf, root, flower) suggesting that DNA methyltransferase genes were probably not themselves targets of uniparental epigenetic silencing for over thousands of generations of allotetraploid evolution. The level of CG and CHG methylation of selected high-copy repeated sequences was similar and high in tobacco and its diploid progenitors. We speculate that natural selection might favor additive expression of parental DNA methyltransferase genes maintaining high levels of DNA methylation in tobacco, which has a repeat-rich heterochromatic genome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.