ArticleMolecular & cellular proteomics : MCP2009
Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.
Article in Molecular & cellular proteomics : MCP, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Analytical applications of gas-phase ion chemistry enabled by mass spectrometry.Analytical methods : advancing methods and applications · 2026Review
- Leveraging Immonium Ions for Targeting Acyl-Lysine Modifications in Proteomic Datasets.Proteomics · 2021Article
- Electron Transfer/Higher Energy Collisional Dissociation of Doubly Charged Peptide Ions: Identification of Labile Protein Phosphorylations.Journal of the American Society for Mass Spectrometry · 2019Article
- Article
- Phosphopeptide Fragmentation and Site Localization by Mass Spectrometry: An Update.Analytical chemistry · 2019Review
- Electron transfer dissociation mass spectrometry of acidic phosphorylated peptides cationized with trivalent praseodymium.Journal of mass spectrometry : JMS · 2018Article
- Improved Sensitivity and Separations for Phosphopeptides using Online Liquid Chromotography Coupled with Structures for Lossless Ion Manipulations Ion Mobility-Mass Spectrometry.Analytical chemistry · 2018Article
- The Impact of Phosphorylation on Electron Capture Dissociation of Proteins: A Top-Down Perspective.Journal of the American Society for Mass Spectrometry · 2017Article
- 193 nm Ultraviolet Photodissociation Mass Spectrometry for Phosphopeptide Characterization in the Positive and Negative Ion Modes.Journal of proteome research · 2016Article
- Ion Activation Methods for Peptides and Proteins.Analytical chemistry · 2016Review
- Article
- Probing the electron capture dissociation mass spectrometry of phosphopeptides with traveling wave ion mobility spectrometry and molecular dynamics simulations.Journal of the American Society for Mass Spectrometry · 2015Article
- Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1.Journal of virology · 2014Article
- Large-scale analysis of peptide sequence variants: the case for high-field asymmetric waveform ion mobility spectrometry.Analytical chemistry · 2013Article
- Protein analysis by shotgun/bottom-up proteomics.Chemical reviews · 2013Review
- Probing the complementarity of FAIMS and strong cation exchange chromatography in shotgun proteomics.Journal of the American Society for Mass Spectrometry · 2013Article
- Conversion of 3-nitrotyrosine to 3-aminotyrosine residues facilitates mapping of tyrosine nitration in proteins by electrospray ionization-tandem mass spectrometry using electron capture dissociation.Journal of mass spectrometry : JMS · 2012Article
- Functional phosphoproteomic mass spectrometry-based approaches.Clinical and translational medicine · 2012Article
- Relevant phosphoproteomic and mass spectrometry: approaches useful in clinical research.Clinical and translational medicine · 2012Article
- Evaluation of front-end higher energy collision-induced dissociation on a benchtop dual-pressure linear ion trap mass spectrometer for shotgun proteomics.Analytical chemistry · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
We used on-line electron capture dissociation (ECD) for the large scale identification and localization of sites of phosphorylation. Each FT-ICR ECD event was paired with a linear ion trap collision-induced dissociation (CID) event, allowing a direct comparison of the relative merits of ECD and CID for phosphopeptide identification and site localization. Linear ion trap CID was shown to be most efficient for phosphopeptide identification, whereas FT-ICR ECD was superior for localization of sites of phosphorylation. The combination of confident CID and ECD identification and confident CID and ECD localization is particularly valuable in cases where a phosphopeptide is identified just once within a phosphoproteomics experiment.
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