Evidence map›Paper›PMID 19129753›Full record

ArticleMucosal immunology2009

Crossing barriers: infections of the lung and the gut.

P J Openshaw

Open access · bronzeAbstract readComment
In one paragraph

Article in Mucosal immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  7. Article
  8. Review
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  11. Article
  12. Review
  13. Implications of SARS-CoV-2 infection for neurogastroenterology.Neurogastroenterology and motility · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Intestinal permeability changes with bacterial translocation as key events modulating systemic host immune response to SARS-CoV-2: A working hypothesis.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

P J OpenshawCentre for Respiratory Infection, Imperial College London, Paddington, London, England. p.openshaw@imperial.ac.uk
Imperial College London · GB

Funding

Medical Research Council MC_G1001212
6 · The paper itself

Abstract

Although known as respiratory pathogens, severe acute respiratory syndrome (SARS) and its sister coronaviruses frequently cause enteric symptoms. In addition, other classically non-enteric viruses (such as HIV and influenza) may also have enteric effects that are crucial in their pathogeneses. These effects can be due to direct infection of the gut mucosa, but can also be because of decreased antibacterial defenses, increased mucosal permeability, bacterial translocation, and systemic leak of endotoxin.

Indexed as

Bacterial InfectionsCoronavirusCoronavirus InfectionsEnteritisGastrointestinal TractHIV-1HIV InfectionsHumansInfluenza, HumanLungPeyer's PatchesSevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirus

Identifiers

PMID19129753
PMCPMC7100545
OpenAlexW1983424061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.