ReviewProceedings. Biological sciences2009
Earthworm genomes, genes and proteins: the (re)discovery of Darwin's worms.
Review in Proceedings. Biological sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- LumbriCyc: towards metabolic modelling of earthworms.NPJ systems biology and applications · 2026Article
- The genome sequence of the common earthworm,Wellcome open research · 2023Article
- Wound healing and Cadmium detoxification in the earthwormFrontiers in immunology · 2023Article
- Amynthas corticis genome reveals molecular mechanisms behind global distribution.Communications biology · 2021Article
- Article
- Cryptic speciation and blurred species boundaries of the earthworm: A challenge for soil-based toxicological risk assessments.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2021Article
- Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration.Nature communications · 2020Article
- Population genetics and diversity structure of an invasive earthworm in tropical and temperate pastures from Veracruz, Mexico.ZooKeys · 2020Article
- Counter effects of Asiaticosids-D through putative neurotransmission on rotenone induced cerebral ganglionic injury inIBRO reports · 2019Article
- Earthworm Lumbricus rubellus MT-2: Metal Binding and Protein Folding of a True Cadmium-MT.International journal of molecular sciences · 2016Article
- An Ancient Divide in a Contiguous Rainforest: Endemic Earthworms in the Australian Wet Tropics.PloS one · 2015Article
- Metallothionein gene expression differs in earthworm populations with different exposure history.Ecotoxicology (London, England) · 2014Article
- Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms.Environmental health perspectives · 2011Review
- Design, validation and annotation of transcriptome-wide oligonucleotide probes for the oligochaete annelid Eisenia fetida.PloS one · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small incremental biological change, winnowed by natural selection over geological time scales to produce large consequences, was Darwin's singular insight that revolutionized the life sciences. His publications after 1859, including the 'earthworm book', were all written to amplify and support the evolutionary theory presented in the Origin. Darwin was unable to provide a physical basis for the inheritance of favoured traits because of the absence of genetic knowledge that much later led to the 'modern synthesis'. Mistaken though he was in advocating systemic 'gemmules' as agents of inheritance, Darwin was perceptive in seeking to underpin his core vision with concrete factors that both determine the nature of a trait in one generation and convey it to subsequent generations. This brief review evaluates the molecular genetic literature on earthworms published during the last decade, and casts light on the specific aspects of earthworm evolutionary biology that more or less engaged Darwin: (i) biogeography, (ii) species diversity, (iii) local adaptations and (iv) sensitivity. We predict that the current understanding will deepen with the announcement of a draft earthworm genome in Darwin's bicentenary year, 2009. Subsequently, the earthworm may be elevated from the status of a soil sentinel to that elusive entity, an ecologically relevant genetic model organism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.