ReviewHuman genomics2008
A survey of genetic simulation software for population and epidemiological studies.
Review in Human genomics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Human ancestries simulation and inference: a review of ancestral recombination graph-based approaches.Frontiers in bioinformatics · 2026Review
- Demes: a standard format for demographic models.Genetics · 2022Article
- Efficient ancestry and mutation simulation with msprime 1.0.Genetics · 2022Article
- AdmixSim 2: a forward-time simulator for modeling complex population admixture.BMC bioinformatics · 2021Article
- OPENMENDEL: a cooperative programming project for statistical genetics.Human genetics · 2020Review
- skelesim: an extensible, general framework for population genetic simulation in R.Molecular ecology resources · 2017Article
- Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes.PLoS computational biology · 2016Article
- Reproducible simulations of realistic samples for next-generation sequencing studies using Variant Simulation Tools.Genetic epidemiology · 2015Article
- Genetic simulation tools for post-genome wide association studies of complex diseases.Genetic epidemiology · 2015Article
- Genetic Simulation Resources: a website for the registration and discovery of genetic data simulators.Bioinformatics (Oxford, England) · 2013Article
- Computer programs and methodologies for the simulation of DNA sequence data with recombination.Frontiers in genetics · 2013Article
- SimRare: a program to generate and analyze sequence-based data for association studies of quantitative and qualitative traits.Bioinformatics (Oxford, England) · 2012Article
- Simulation of molecular data under diverse evolutionary scenarios.PLoS computational biology · 2012Article
- Computer simulations: tools for population and evolutionary genetics.Nature reviews. Genetics · 2012Review
- A comparison of gene region simulation methods.PloS one · 2012Article
- Next generation analytic tools for large scale genetic epidemiology studies of complex diseases.Genetic epidemiology · 2012Article
- Simulation of genes and genomes forward in time.Current genomics · 2010Article
- Simulating sequences of the human genome with rare variants.Human heredity · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A number of programs have been developed for simulating population genetic and genetic epidemiological data conforming to one of three main algorithmic approaches: 'forwards', 'backwards' and 'sideways'. This review aims to make the reader aware of the range of options currently available to them. While no one program emerges as the best choice in all circumstances, we nominate a set of those which currently appear most promising.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.