ArticleNano letters2009
Remote optical switch for localized and selective control of gene interference.
Article in Nano letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed.
- Artificial biomarker-based feedback-regulated personalized and precise thrombolysis with lower hemorrhagic risk.Science advances · 2025Article
- Applications of Gold Nanoparticles in Plasmonic and Nanophotonic Biosensing.Advances in biochemical engineering/biotechnology · 2024Review
- Phase intensity nanoscope (PINE) opens long-time investigation windows of living matter.Nature communications · 2023Article
- Nanoparticles for Interrogation of Cell Signaling.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023Review
- Design of a nanobiosystem with remote photothermal gene silencing in Chlamydomonas reinhardtii to increase lipid accumulation and production.Microbial cell factories · 2023Article
- Optical Penetration of Shape-Controlled Metallic Nanosensors across Membrane Barriers.Sensors (Basel, Switzerland) · 2023Article
- Neural modulation with photothermally active nanomaterials.Nature reviews bioengineering · 2023Article
- Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination.Molecules (Basel, Switzerland) · 2023Review
- Intelligent Fusion Imaging Photonics for Real-Time Lighting Obstructions.Sensors (Basel, Switzerland) · 2022Article
- Dynamic observations of CRISPR-Cas target recognition and cleavage heterogeneities.Nanophotonics (Berlin, Germany) · 2022Article
- Recent Advances in Nanomicelles Delivery Systems.Nanomaterials (Basel, Switzerland) · 2020Review
- Development of a Theoretical Model That Predicts Optothermal Energy Conversion of Gold Metallic Nanoparticles.ACS omega · 2020Article
- Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts.Chemical reviews · 2018Review
- Gold Nanorod-Based Engineered Cardiac Patch for Suture-Free Engraftment by Near IR.Nano letters · 2018Article
- Evaluating the Mechanisms of Light-Triggered siRNA Release from Nanoshells for Temporal Control Over Gene Regulation.Nano letters · 2018Article
- DNA-Assembled Advanced Plasmonic Architectures.Chemical reviews · 2018Review
- Photothermal fabrication of microscale patterned DNA hydrogels.Royal Society open science · 2018Article
- Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis.Nature communications · 2018Article
- Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells.Journal of controlled release : official journal of the Controlled Release Society · 2017Article
- Gold nanoparticle-mediated photothermal therapy: applications and opportunities for multimodal cancer treatment.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Near infrared-absorbing gold nanoplasmonic particles (GNPs) are used as optical switches of gene interference and are remotely controlled using light. We have tuned optical switches to a wavelength where cellular photodamage is minimized. Optical switches are functionalized with double-stranded oligonucleotides. At desired times and at specific intracellular locations, remote optical excitation is used to liberate gene-interfering oligonucleotides. We demonstrate a novel gene-interfering technique offering spatial and temporal control, which is otherwise impossible using conventional gene-interfering techniques.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.