ArticleMusculoskeletal care2009
The impact of patient-perceived restricted access to anti-TNF therapy for rheumatoid arthritis: a qualitative study.
Article in Musculoskeletal care, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Patients' Attitudes and Experiences of Disease-Modifying Antirheumatic Drugs in Rheumatoid Arthritis and Spondyloarthritis: A Qualitative Synthesis.Arthritis care & research · 2018Pooled it
- UK-South Asian patients' experiences of and satisfaction toward receiving information about biologics in rheumatoid arthritis.Patient preference and adherence · 2018Article
- Evaluation of a novel autoinjector for subcutaneous self-administration of belimumab in systemic lupus erythematosus .International journal of clinical pharmacology and therapeutics · 2016Article
- Openness to and preference for attributes of biologic therapy prior to initiation among patients with rheumatoid arthritis: patient and rheumatologist perspectives and implications for decision making.Patient preference and adherence · 2016Article
- The design of a low literacy decision aid about rheumatoid arthritis medications developed in three languages for use during the clinical encounter.BMC medical informatics and decision making · 2014Article
- A Q-methodology study of flare help-seeking behaviours and different experiences of daily life in rheumatoid arthritis.BMC musculoskeletal disorders · 2014Article
- Thoughts and perceptions of ankylosing spondylitis patients with regard to TNF inhibitors.Rheumatology international · 2014Article
- Patient experiences, attitudes and expectations towards receiving information about anti-TNF medication--"It could give me two heads and I'd still try it!".BMC musculoskeletal disorders · 2013Article
- Patients' independence of a nurse for the administration of subcutaneous anti-TNF therapy: A phenomenographic study.International journal of qualitative studies on health and well-being · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo explore rheumatoid arthritis (RA) patients' experience of access to anti-tumour necrosis factor (anti-TNF) therapy in the UK, and of switching therapies after an initial failure.
methodsPatients were asked about their experience of accessing, receiving and discontinuing anti-TNF therapy in face-to-face indepth interviews, within the context of the larger study about treatment outcomes. Seventeen individuals with a diagnosis of RA and experience of receiving anti-TNF therapy were interviewed in one hospital trust in England.
resultsDifferent emotions (Theme 1) surrounded the process of accessing anti-TNF therapy: hope, desperation, apprehension, anxiety and frustration. Experience of receiving anti-TNF therapy (Theme 2) included not only positive transformation, but also fear of failure and discontinuation. The subsequent value that patients placed on anti-TNF therapy (Theme 3) included having a right to receive therapy and being lucky. These three themes were underpinned by the core category of 'willing to try anything'. Those switching therapies reported increased caution over the possibility of recurring side effects, but some suggestion of benefit. There was a perception that access to anti-TNF therapy was restricted by cost, rather than being recommended for those in clinical need.
conclusionsAnti-TNF therapies may have a sudden and dramatic impact on RA patients' lives that contrast with other available medications. However, the stress of the patient's journey through the need to 'qualify' for anti-TNF therapy, and the fear of failing or discontinuation of therapy, should not be underestimated by clinicians.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.