Evidence map›Paper›PMID 19127340›Full record

ArticleThe Korean journal of parasitology2008

Malondialdehyde, glutathione, and nitric oxide levels in Toxoplasma gondii seropositive patients.

Ulku Karaman, Tuncay Celik, Tugba Raika Kiran, Cemil Colak, Nilgun Ulfet Daldal

Open access · bronzeAbstract read
In one paragraph

Article in The Korean journal of parasitology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Potential effects of alpha-pinene, a monoterpene commonly found in essential oils againstJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Role of oxidative stress in the pathophysiology of Toxoplasma gondii infection.International journal of immunopathology and pharmacology · 2016
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Anti-Iranian journal of parasitology
    Article
  18. Iranian journal of parasitology
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ulku KaramanInonu University School of Medicine, Department of Parasitology, Malatya, Turkey.
Tuncay Celik
Tugba Raika Kiran
Cemil Colak
Nilgun Ulfet Daldal
Inonu University · TRFırat University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the difference in the serum malondialdehyde (MDA), glutathione (GSH), and nitric oxide (NO) levels between normal and T. gondii-infected patients. To this end, MDA, GSH, and NO levels in the sera of 37 seropositive patients and 40 participants in the control group were evaluated. In Toxoplasma ELISA, IgG results of the patient group were 1,013.0 +/- 543.8 in optical density (mean +/- SD). A statistically significant difference was found between patients and the control group in terms of MDA, GSH, and NO levels. A decrease in GSH activity was detected, while MDA and NO levels increased significantly. Consequently, it is suggested that the use of antioxidant vitamins in addition to a parasite treatment shall prove useful. The high infection vs control ratio of MDA and NO levels probably suggests the occurrence as a mechanism of tissue damage in cases of chronic toxoplasmosis. Moreover, it is recommended that the patient levels of MDA, GSH, and NO should be evaluated in toxoplasmosis.

Indexed as

AnimalsGlutathioneHumansImmunity, CellularLipid PeroxidationMalondialdehydeNitric OxideOxidative StressToxoplasmaToxoplasmosisGlutathioneMalondialdehydeNitric Oxideglutathionemalondialdehydenitric oxideToxoplasma gondii

Identifiers

PMID19127340
PMCPMC2612619
OpenAlexW1996813232

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.