Evidence map›Paper›PMID 19127305›Full record

ArticleEpilepsy currents

Effects of in utero antiepileptic drug exposure.

Kimford J Meador

Open access · greenAbstract read
In one paragraph

Article in Epilepsy currents. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. A description of sodium valproate, lamotrigine and levetiracetam consumption in the Western Cape public sector.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022
    Observational
  5. Article
  6. Review
  7. Review
  8. Teratogenicity of Antiepileptic Drugs.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2017
    Article
  9. Review
  10. Article
  11. Teratogenic effects of pregabalin in mice.Iranian journal of basic medical sciences · 2013
    Article
  12. Article
  13. Epilepsy drugs and effects on fetal development: Potential mechanisms.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012
    Article
  14. Treatment options in juvenile myoclonic epilepsy.Current treatment options in neurology · 2011
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Kimford J MeadorDepartment of Neurology, University of Florida, McKnight Brain Institute Gainesville, Florida, USA. kimford.meador@neurology.ufl.edu
University of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies demonstrate an increased teratogenic risk for valproate and a probable increased risk for phenobarbital. Carbamazepine and lamotrigine appear relatively safe; however, results are inconclusive concerning a specific risk for cleft lip/palate for both drugs as well as a dose-dependent effect for malformations associated with lamotrigine. Data regarding teratogenic risks for other antiepileptic drugs are inadequate. Additional studies are needed to delineate further the risks for all antiepileptic drugs and determine the underlying mechanisms.

Identifiers

PMID19127305
PMCPMC2610228
OpenAlexW2167715759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.