Evidence map›Paper›PMID 19126962›Full record

ReviewCancer biomarkers : section A of Disease markers2008

In vivo cancer biomarkers of esophageal neoplasia.

Shaoying Lu, Thomas D Wang

Open access · greenAbstract readReview
In one paragraph

Review in Cancer biomarkers : section A of Disease markers, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Targeted endoscopic imaging.Gastrointestinal endoscopy clinics of North America · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Shaoying LuDepartment of General Surgery, First Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an Shaanxi, People's Republic of China.
Thomas D Wang
First Affiliated Hospital of Xi'an Jiaotong University · CNUniversity of Michigan–Ann Arbor · US

Funding

MICHIGAN INSTITUTE FOR CLINICAL AND HEALTH RESEARCH (MICHR) (UL1): (BPCA)UL1RR024986 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHANLEY, THOMAS P. · 2007 to 2011
$51.2M
Task Specific Project 4U54CA136429 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI REHEMTULLA, ALNAWAZ · 2008 to 2012
$5.2M
Miniature Confocal Theta Flourescence MicroscopeR33CA109988 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, THOMAS D · 2005 to 2007
$1.1M
Novel Confocal Microscope for Molecular/Cellular ImagingK08DK067618 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, THOMAS D · 2003 to 2007
$607k
NCI NIH HHS R33 CA109988NCI NIH HHS U54 CA136429NCRR NIH HHS UL1 RR024986NIDDK NIH HHS K08 DK067618
6 · The paper itself

Abstract

The emergence of in vivo cancer biomarkers is promising tool for early detection, risk stratification, and therapeutic intervention in the esophagus, where adenocarcinoma is increasing at a rate that is faster than any other in industrialized nations. Exciting advances in target identification, probe development, and optical instrumentation are creating tremendous new opportunities for advancing techniques of molecular imaging. Progress in these areas is being made with small animal models of esophageal cancer using surgical approaches to induce reflux of acid and bile, and these findings are beginning to be evaluated in the clinic. Further identification of relevant targets, characterization of specific probes, and development of endoscopic imaging technologies are needed to further this direction in the field of molecular medicine. In the future, new methods that use in vivo cancer biomarkers for the early detection of neoplastic changes in the setting of Barrett's esophagus will become available.

Indexed as

Molecular Probe TechniquesAdenocarcinomaAnimalsBiomarkers, TumorEsophageal NeoplasmsHumansBiomarkers, Tumor

Identifiers

PMID19126962
PMCPMC3226753
OpenAlexW1625347561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.