ArticleCerebral cortex (New York, N.Y. : 1991)2009
Role of corticospinal suppression during motor preparation.
Article in Cerebral cortex (New York, N.Y. : 1991), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
110 citing papers in PubMed, 1 synthesis or guideline pooled it, 224 citations in OpenAlex.
- Evidence for non-selective response inhibition in uncertain contexts revealed by combined meta-analysis and Bayesian analysis of fMRI data.Scientific reports · 2022Pooled it
- The aging motor system as a model for plastic changes of GABA-mediated intracortical inhibition and their behavioral relevance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- Premovement Suppression of Corticospinal Excitability Is Modulated by Reaction Time Task Requirements.The European journal of neuroscience · 2026Article
- Very low-amplitude muscle activity increases probability of motor evoked potentials in healthy individuals and in amyotrophic lateral sclerosis.Experimental physiology · 2026Article
- A method of compensating for the excitability of spinal motoneurones when estimating the magnitude of potentials evoked in skeletal muscles.The Journal of physiology · 2026Article
- Global executive function advantages in older adults with long-term habitual exercise are associated with resting-state functional reorganization.GeroScience · 2026Article
- Correlated amplitudes of potentials evoked in homologous muscles by magnetic stimulation reveal positive covariation of corticospinal output.Experimental physiology · 2026Article
- Respiratory and Cardiac Phase Coupling With Voluntary Actions Across Motor Tasks.Psychophysiology · 2026Article
- Motor Intention Drives Corticospinal Facilitation during Interception Planning.bioRxiv : the preprint server for biology · 2026Article
- Central autonomic network dysfunction in Stroke-Heart Syndrome: mechanistic roles of the insula and limbic system.Frontiers in neuroscience · 2026Review
- Enhancing cognitive and motor performance through mental training: The interplay between temporal preparation, inhibition and autonomic arousal.Cognitive, affective & behavioral neuroscience · 2025Article
- Article
- Corticospinal excitability during timed interception depends on the speed of the moving target.Journal of neurophysiology · 2025Article
- Cerebellar Brain Inhibition and Its Association with Motor Inhibition and Reaction Time In Younger and Older Adults.Cerebellum (London, England) · 2025Article
- Preparing to act follows Bayesian inference rules.iScience · 2025Article
- The Hippocampus Preorders Movements for Skilled Action Sequences.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Examining motor evidence for the pause-then-cancel model of action-stopping: insights from motor system physiology.Journal of neurophysiology · 2024Article
- Modulation of intracortical circuits in primary motor cortex during automatic action tendencies.Brain structure & function · 2024Article
- Examining motor evidence for the pause-then-cancel model of action-stopping: Insights from motor system physiology.bioRxiv : the preprint server for biology · 2024Article
- Neurofeedback-induced desynchronization of sensorimotor rhythm elicits pre-movement downregulation of intracortical inhibition that shortens simple reaction time in humans: A double-blind, sham-controlled randomized study.Imaging neuroscience (Cambridge, Mass.) · 2024Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Behavior arises from a constant competition between potential actions. For example, movements performed unimanually require selecting one hand rather than the other. Corticospinal (CS) excitability of the nonselected hand is typically decreased prior to movement initiation, suggesting that response selection may involve mechanisms that inhibit nonselected candidate movements. To examine this hypothesis, participants performed a reaction time task, responding with the left, right, or both indexes. Transcranial magnetic stimulation was applied over the right primary motor cortex (M1) to induce motor-evoked potentials (MEPs) in a left hand muscle at various stages during response preparation. To vary the time of response selection, an imperative signal was preceded by a preparatory cue that was either informative or uninformative. Left MEPs decreased following the cue. Surprisingly, this decrease was greater when an informative cue indicated that the response might require the left hand than when it indicated a right hand response. In the uninformative condition, we did not observe additional attenuation of left MEP after an imperative indicating a right hand response. These results argue against the "deselection" hypothesis. Rather, CS suppression seems to arise from "impulse control" mechanisms that ensure that responses associated with potentially selected actions are not initiated prematurely.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.