ArticleBosnian journal of basic medical sciences2008
Congenital malformations of the central nervous system: clinical approach.
Article in Bosnian journal of basic medical sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 48 citations in OpenAlex.
- Congenital Anomaly Prevalence: A 10-Year Retrospective Study in a Tertiary Hospital in Turkey.Birth defects research · 2026Article
- Epidemiological Patterns of Neurological and Neuromuscular Disorders in the Potohar Region of Pakistan.Clinical medicine insights. Pediatrics · 2026Article
- Successful Management of a Rare Case of Double Myelomeningocele in an Infant: A Case Report from Pakistan and Brief Review of Pathophysiology.Asian journal of neurosurgery · 2025Article
- Congenital interparietal encephalocele with porencephlacic cyst: A case report.Radiology case reports · 2025Article
- Acrania with exencephaly and spinal Myeloschisis in a young pregnant woman from Rural Nepal: A curious case report.Radiology case reports · 2025Article
- Article
- Evaluation of prenatal central nervous system anomalies: obstetric management, fetal outcomes and chromosome abnormalities.BMC pregnancy and childbirth · 2022Article
- Atretic Parietal Cephalocele With First Trimester Chiari Malformation and Sinus Pericranii Companion Case.Cureus · 2022Article
- Clinical Utility and the Yield of Single Nucleotide Polymorphism Array in Prenatal Diagnosis of Fetal Central Nervous System Abnormalities.Frontiers in molecular biosciences · 2021Article
- The Spectrum of Congenital Central Nervous System Anomalies Among Stillborn: An Autopsy Based Study.Annals of neurosciences · 2020Article
- Major birth defects in the Brazilian side of the triple border: a population-based cross-sectional study.Archives of public health = Archives belges de sante publique · 2020Article
- Temporal arachnoid cysts: are they congenital?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- Influence of congenital central nervous system malformations on postoperative complications following placement of cerebrospinal fluid shunts in pediatric and adolescent patients.Wiener klinische Wochenschrift · 2014Article
- Prevention of myelomeningocele: African perspectives.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013Review
- Prenatal neurologic anomalies: sonographic diagnosis and treatment.Paediatric drugs · 2012Review
- Imaging the fetal central nervous system.Facts, views & vision in ObGyn · 2011Review
- Central nervous system congenital malformations in a developing country: issues and challenges against their prevention.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2010Article
- Two Cases of Craniospinal Rachischisis Totalis: Role of Magnetic Resonance Imaging in Diagnosis and Review of Neural Tube Defects in the Indian Context with Implications for Folate Fortification.Journal of pediatric neurosciencesArticle
- Epidemiology of congenital anomalies of the central nervous system in children in Enugu, Nigeria: A retrospective study.Annals of African medicineArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central nervous system (CNS) malformations represent important factor of morbidity and mortality in children. The aim of the study was to determine the incidence, type and clinical features of CNS malformations in children who were admitted at the Neonatal and Child Neurology Department, Neonatal Intensive Care Unit and Paediatric Intensive Care Unit of Paediatric Clinic, University of Sarajevo Clinics Centre, from January 1st, 2002 to December 31st, 2006. There were total of 16520 admissions at the Paediatric Clinic over the studied period. CNS malformations, solitary or multiple, have been diagnosed in 100 patients (0,61%). The total number of various CNS malformations was 127. Lethal outcome was established in 9/100 cases (9%). The most frequent CNS malformations were neural tube defects 49/127 (38,6%). Hydrocephalus was seen in 34/127 (26,8%), microcephaly in 24/127 (18,9%), agenesis of corpus callosum in 10/127 (7,9%), Dandy Walker malformation in 6/127 (4,7%) and other CNS malformations in 4/127 (3,1%). In 20/100 of patients neural tube defect was associated with hydrocephalus (20%). CNS malformations were prenatally diagnosed in 13/100 of patients (13%). Primary prevention of CNS malformations can be improved in our country by better implementation of preconceptional folic acid therapy for all women of childbearing age. Secondary prevention by prenatal diagnosis requires advanced technical equipment and adequate education of physicians in the field of foetal ultrasonography. In our circumstances, prenatal diagnostics of CNS malformations is still not developed enough.
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