Evidence map›Paper›PMID 19125310›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Vascular dysfunction measured by fingertip thermal monitoring is associated with the extent of myocardial perfusion defect.

Naser Ahmadi, Nudrat Usman, John Shim, Vivek Nuguri, Panukorn Vasinrapee, Fereshteh Hajsadeghi, Zhiying Wang, Gary P Foster, Khurram Nasir, Harvey Hecht and 2 more

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Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Elevated serum thyrotropin levels and endothelial dysfunction in a prospective hemodialysis cohort.Hemodialysis international. International Symposium on Home Hemodialysis · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Fingertip digital thermal monitoring: a fingerprint for cardiovascular disease?The international journal of cardiovascular imaging · 2010
    Article
  8. Can a simple fingertip temperature measurement predict a cardiac event?The international journal of cardiovascular imaging · 2009
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Naser AhmadiLos Angeles Biomedical Research Institute, Harbor UCLA Medical Center, 1124 W. Carson Street, RB2, Torrance, CA 90502, USA.
Nudrat Usman
John Shim
Vivek Nuguri
Panukorn Vasinrapee
Fereshteh Hajsadeghi
Zhiying Wang
Gary P Foster
Khurram Nasir
Harvey Hecht
Morteza Naghavi
Matthew Budoff

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have shown that vascular dysfunction measured by digital thermal monitoring (DTM) during an arm-cuff reactive hyperemia procedure correlates with the severity of coronary artery disease measured by coronary artery calcium in asymptomatic patients. Current study investigates the correlation between DTM and abnormal myocardial perfusion imaging (MPI).

methodsAbout 116 consecutive patients with chest discomfort, age 57 +/- 10 years, underwent MPI, DTM and Framingham Risk Score (FRS) assessment. Fingertip temperature rebound (TR), DTM index of vascular reactivity, was assessed after a 2-minute arm-cuff reactive hyperemia test. The extent of myocardial perfusion defect was measured by summed stress score (SSS).

resultsTR decreased from SSS < 4 (1.61 +/- 0.15) to 4 < or = SSS < or = 8 (0.5 +/- 0.22) to 9 < or = SSS < or = 13 (0.26 +/- 0.15) to SSS > 13 (-0.37 +/- 0.19) (P = .0001). After adjusting for cardiac risk factors, the odds ratio of the lowest versus two upper tertiles of TR was 3.93 for SSS > or = 4 and 9.65 for SSS > or = 8 compared to SSS < 4. TR correlated well with SSS (r = -0.88, P = .0001). Addition of TR to FRS increased the area under the ROC curve to predict abnormal MPI, SSS > or = 4, from 0.65 to 0.84 (P < .05).

conclusionVascular dysfunction measured by DTM is associated with the extent of myocardial perfusion defect independent of age, gender, and cardiac risk factors.

Indexed as

Coronary Artery DiseaseFemaleFingersHumansMaleMiddle AgedMyocardial Perfusion ImagingPeripheral Vascular DiseasesStatistics as TopicThermographyTomography, Emission-Computed, Single-Photon

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.