Clinical Use of PPARgamma Ligands in Cancer.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

1. PPAR-γ in Melanoma and Immune Cells: Insights into Disease Pathogenesis and Therapeutic Implications.Cells · 2025
   Review
2. PPARγ activation modulates the balance of peritoneal macrophage populations to suppress ovarian tumor growth and tumor-induced immunosuppression.Journal for immunotherapy of cancer · 2023
   Article
3. Histone methyltransferase KMT2D mediated lipid metabolism via peroxisome proliferator-activated receptor gamma in prostate cancer.Translational cancer research · 2022
   Article
4. Engaging plasticity: Differentiation therapy in solid tumors.Frontiers in pharmacology · 2022
   Review
5. Differential Effects of Cancer-Associated Mutations Enriched in Helix H3 of PPARγ.Cancers · 2020
   Article
6. The PPARγ Agonist Rosiglitazone Suppresses Syngeneic Mouse SCC (Squamous Cell Carcinoma) Tumor Growth through an Immune-Mediated Mechanism.Molecules (Basel, Switzerland) · 2019
   Article
7. PPARγ Contributes to Immunity Induced by Cancer Cell Vaccines That Secrete GM-CSF.Cancer immunology research · 2018
   Article
8. Epidermal PPARγ influences subcutaneous tumor growth and acts through TNF-α to regulate contact hypersensitivity and the acute photoresponse.Oncotarget · 2017
   Article
9. Rosiglitazone reduces breast cancer risk in Taiwanese female patients with type 2 diabetes mellitus.Oncotarget · 2017
   Article
10. Effects of Ranolazine on Astrocytes and Neurons in Primary Culture.PloS one · 2016
    Article
11. Inverse association of colorectal cancer prevalence to serum levels of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in a large Appalachian population.BMC cancer · 2014
    Article
12. PPARγ agonists target aromatase via both PGE2 and BRCA1.Cancer prevention research (Philadelphia, Pa.) · 2012
    Article
13. Targeting PPARγ Signaling Cascade for the Prevention and Treatment of Prostate Cancer.PPAR research · 2012
    Article
14. PPARs: Interference with Warburg' Effect and Clinical Anticancer Trials.PPAR research · 2012
    Article
15. Metabolic effects of pioglitazone in chemically-induced mammary carcinogenesis in rats.Pathology oncology research : POR · 2011
    Article
16. Inhalation delivery of a novel diindolylmethane derivative for the treatment of lung cancer.Molecular cancer therapeutics · 2010
    Article
17. Anticancer Role of PPARgamma Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes.PPAR research · 2010
    Article
18. PPAR-γ agonists and their effects on IGF-I receptor signaling: Implications for cancer.PPAR research · 2009
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors at 1 institution in 1 country.

Funding

Abstract