Trial reportJournal of clinical epidemiology2009
Response analysis for multiple symptoms revealed differences between arms of a symptom management trial.
Trial report in Journal of clinical epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Telephone interventions for symptom management in adults with cancer.The Cochrane database of systematic reviews · 2020Pooled it
- Automated telephone communication systems for preventive healthcare and management of long-term conditions.The Cochrane database of systematic reviews · 2016Pooled it
- A literature synthesis of symptom prevalence and severity in persons receiving active cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Pooled it
- An integrated model of multimorbidity and symptom science.Nursing outlookPooled it
- Symptom management interventions influence unscheduled health services use among cancer survivors and caregivers.Journal of cancer survivorship : research and practice · 2026Trial
- A sequential multiple assignment randomized trial of symptom management for cancer survivors during treatment and their informal caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Trial
- A Sequential Multiple Assignment Randomized Trial of Symptom Management After Chemotherapy.Journal of pain and symptom management · 2023Trial
- Family caregivers of those with cancer: quality of life outcomes from a sequential multiple assignment randomized trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Trial
- Reflexology and meditative practices for symptom management among people with cancer: Results from a sequential multiple assignment randomized trial.Research in nursing & health · 2021Trial
- Symptom response analysis of a randomized controlled trial of reflexology for symptom management among women with advanced breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Trial
- Using SMART design to improve symptom management among cancer patients: A study protocol.Research in nursing & health · 2017Trial
- Testing the differential effects of symptom management interventions in cancer.Psycho-oncology · 2015Trial
- Deconstruction of nurse-delivered patient self-management interventions for symptom management: factors related to delivery enactment and response.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2010Trial
- Baseline self-efficacy and engagement in a symptom management intervention after cancer treatment: an exploratory analysis of a sequential multiple assignment randomized trial.Journal of cancer survivorship : research and practice · 2026Article
- Predictors of persistence of post-chemotherapy symptoms among survivors of solid tumor cancers.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Article
- Fatigue in family caregivers of adult intensive care unit survivors.Journal of pain and symptom management · 2014Article
- Self-reported physical symptoms in intensive care unit (ICU) survivors: pilot exploration over four months post-ICU discharge.Journal of pain and symptom management · 2014Article
- A nonparametric test for equality of survival medians.Statistics in medicine · 2012Article
- Technology and quality of life outcomes.Seminars in oncology nursing · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo describe the methodology of evaluating the response of cancer patients to interventions directed at lowering severity of multiple symptoms, and to compare two arms of a symptom management trial to determine factors associated with response and time to response. STUDY DESIGN AND
settingRandomized trial comparing a nurse-assisted symptom management (NASM) cognitive-behavioral intervention with an automated telephone symptom management (ATSM). Patients in both arms received six intervention contacts over 8 weeks. Analyses of the intervention contact data for 190 patients in NASM arm and 164 patients in the ATSM arm were conducted. Severities of 15 cancer-related symptoms were assessed at each intervention contact, and an anchor-based definition of response was adopted. Analyses were carried out using generalized estimating equations and Cox marginal proportional hazard models.
resultsWhen compared with patients in the NASM, patients in the ATSM had better response to manage anxiety, depression, poor appetite, cough, and fatigue. NASM was more successful in managing cancer pain. Response and time to response were associated with several patient and disease characteristics.
conclusionThe approach described here presents an analytic and clinical improvement over methods that examine each symptom separately or use summed scores of severity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.