Evidence map›Paper›PMID 19123124›Full record

ReviewThe International journal of developmental biology2009

Ocular forkhead transcription factors: seeing eye to eye.

Holly E Moose, Lisa E Kelly, Srivamsi Nekkalapudi, Heithem M El-Hodiri

Abstract readReview
In one paragraph

Review in The International journal of developmental biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Holly E MooseIntegrated Biomedical Sciences Graduate Program, College of Medicine, The Ohio State University, Columbus, OH 43205, USA.
Lisa E Kelly
Srivamsi Nekkalapudi
Heithem M El-Hodiri

Funding

The Role of Rx in Retinal Progenitor Cell DevelopmentR01EY015480 · NEI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI EL-HODIRI, HEITHEM M · 2004 to 2015
$3.7M
NEI NIH HHS EY015480NEI NIH HHS R01 EY015480
6 · The paper itself

Abstract

Forkhead transcription factors comprise a large family of proteins with diverse functions during development. Recently, there has been accumulating evidence that several members of this family of proteins play an important role in the development of the vertebrate retina. Here, we summarize the cumulative data which demonstrates the integral role that forkhead factors play in cell cycle control of retinal precursors, as well as in cell fate determination, during retinal development. The expression patterns for 14 retinal expressed forkhead transcription factors are presented with an emphasis on comparing the expression profiles across species. The functional data regarding forkhead gene products expressed within the retina are discussed. As presented, these data suggest that forkhead gene products contribute to the complex regulation of proliferation and differentiation of retinal precursors during vertebrate eye development.

Indexed as

AnimalsEyeForkhead Transcription FactorsGene Expression Regulation, DevelopmentalHumansOrgan SpecificityStem CellsForkhead Transcription Factors

Identifiers

PMID19123124
PMCPMC6326383

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.