ArticleJournal of molecular evolution2009
Symbiobacterium lost carbonic anhydrase in the course of evolution.
Article in Journal of molecular evolution, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Physiological Roles of Carbonic Anhydrases and an MpsAB-like Bicarbonate Transporter inbioRxiv : the preprint server for biology · 2026Article
- Genomic and metagenomic survey of microbial carbonic anhydrase genes reveals novel clades, high diversity, and biome specificity.ISME communications · 2026Article
- The COVeterinary research · 2018Article
- Clustering of two genes putatively involved in cyanate detoxification evolved recently and independently in multiple fungal lineages.Genome biology and evolution · 2015Article
- On the molecular mechanism of GC content variation among eubacterial genomes.Biology direct · 2012Article
- Dispensabilities of carbonic anhydrase in proteobacteria.International journal of evolutionary biology · 2012Article
- Unique Evolution of Symbiobacterium thermophilum Suggested from Gene Content and Orthologous Protein Sequence Comparisons.International journal of evolutionary biology · 2010Article
- Phylogenetic and Guanine-Cytosine Content Analysis of Symbiobacterium thermophilum Genes.International journal of evolutionary biology · 2010Article
- Evolution of carbonic anhydrases in fungi.Current genetics · 2009Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent genetic studies have elucidated that carbonic anhydrase (CA; EC 4.2.1.1), a ubiquitous enzyme catalyzing interconversion between CO(2) and bicarbonate, is essential for microbial growth under ambient air but not under high-CO(2) air. The irregular distribution of the phylogenetically distinct types of CA in the prokaryotic genome suggests its complex evolutionary history in prokaryotes. This paper deals with the genetic defect of CA in Symbiobacterium thermophilum, a syntrophic bacterium that effectively grows on CO(2) generated by other bacteria. Phylogenetic analysis based on 31 ribosomal protein sequences demonstrated the affiliation of Symbiobacterium with the class Clostridia with 100% bootstrap support. The phylogeny of beta- and gamma-type CA distributed among Clostridia supported the view that S. thermophilum and several related organisms lost this enzyme during the course of evolution. The loss of CA could be based on the availability of a high level of CO(2) in their living environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.