ArticleThe Plant cell2009
MYB58 and MYB63 are transcriptional activators of the lignin biosynthetic pathway during secondary cell wall formation in Arabidopsis.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 389 papers.
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Who cites it
389 citing papers in PubMed, 872 citations in OpenAlex.
- Integrative QTL mapping and transcriptomic profiling uncover molecular mechanisms underlying lodging resistance inHorticulture research · 2026Review
- High-Density Genome-Wide Association Mapping Identifies Candidate Loci Associated with Maize Stalk Cell Wall Composition.Plants (Basel, Switzerland) · 2026Article
- PgZHD18-PgWDR5b increases basal thermotolerance in Physalis grisea by lignin biosynthesis dependent on H3K4me3.The Plant journal : for cell and molecular biology · 2026Article
- Knockout of RRS1 Enhances Culm Mechanical Strength and Grain Yield in Rice.Plant, cell & environment · 2026Article
- CbuBIM1 Antagonizes CbuMYB27 to Regulate Tension Wood Formation in Catalpa bungei.Plant, cell & environment · 2026Article
- Dynamics of Functional Traits and Molecular Regulation in the Vascular Cambium Across Different Ages ofPlants (Basel, Switzerland) · 2026Article
- The Dual Role of Lignin in Fruit Trees: Unraveling Regulatory Networks from Stress Resilience to Quality Control.Plants (Basel, Switzerland) · 2026Review
- Genetic architecture and major genes for tuber skin texture in potato.Horticulture research · 2026Article
- Genome-Wide Study of MYB Transcription Factors in Maize and Their Essential Roles in Male Fertility and Other Biological Processes.International journal of molecular sciences · 2026Article
- Gallic Acid-Responsive microRNAs Reprogram Lignification During Drought Acclimation Process in Spearmint.Plant biotechnology journal · 2026Article
- Differences in lignification between hulled and hull-less Cucurbita pepo and functional identification of the key regulatory factor CpMYB52.Plant cell reports · 2026Article
- Genome-Wide Identification of the R2R3-MYB Gene Family Members in Masson Pine and the Regulation of Secondary Cell Wall Formation and Lignin Biosynthesis byPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Analysis of the Cinnamoyl-CoA Reductase (CCR) Gene Family and Its Involvement in Lignin Biosynthesis and Stress Responses in Six Tea Plant Cultivars.International journal of molecular sciences · 2026Article
- Physiological and transcriptomic analyses for assessing the effects of uniconazole on female ear development in maize (Zea Mays L.).BMC plant biology · 2026Article
- Genome-wide analysis of the R2R3-MYB family reveals potential regulators of lignin and tricin metabolism in the model grass Setaria viridis.Molecular genetics and genomics : MGG · 2026Article
- Bi-functional transcription factor FnZHD9 regulates leaf curling and drought resistance in fragaria nilgerrensis.BMC plant biology · 2026Article
- Regulatory Roles of MYB Transcription Factors in Root Barrier Under Abiotic Stress.Plants (Basel, Switzerland) · 2026Review
- Integrative transcriptome-metabolome dissection of the molecular basis of lodging resistance in oat (Avena sativa L.) basal internodes.BMC plant biology · 2026Article
- Metabolic engineering strategies for optimized lignan production in plants.Frontiers in plant science · 2026Review
- Comparative transcriptome analysis revealed that tomato response to salt stress induced by exogenous GABA and functional verification of SlGAD1.BMC plant biology · 2025Article
329 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has previously been shown that SECONDARY WALL-ASSOCIATED NAC DOMAIN PROTEIN1 (SND1) is a key transcription factor regulating secondary cell wall formation, including the biosynthesis of cellulose, xylan, and lignin. In this study, we show that two closely related SND1-regulated MYB transcription factors, MYB58 and MYB63, are transcriptional regulators specifically activating lignin biosynthetic genes during secondary wall formation in Arabidopsis thaliana. MYB58 and MYB63 are phylogenetically distinct from previously characterized MYBs shown to be associated with secondary wall formation or phenylpropanoid metabolism. Expression studies showed that MYB58 and MYB63 are specifically expressed in fibers and vessels undergoing secondary wall thickening. Dominant repression of their functions led to a reduction in secondary wall thickening and lignin content. Overexpression of MYB58 and MYB63 resulted in specific activation of lignin biosynthetic genes and concomitant ectopic deposition of lignin in cells that are normally unlignified. MYB58 was able to activate directly the expression of lignin biosynthetic genes and a secondary wall-associated laccase (LAC4) gene. Furthermore, the expression of MYB58 and MYB63 was shown to be regulated by the SND1 close homologs NST1, NST2, VND6, and VND7 and their downstream target MYB46. Together, our results indicate that MYB58 and MYB63 are specific transcriptional activators of lignin biosynthesis in the SND1-mediated transcriptional network regulating secondary wall formation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.