ArticleMolecular ecology2008
Inferring the history of speciation in house mice from autosomal, X-linked, Y-linked and mitochondrial genes.
Article in Molecular ecology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
116 citing papers in PubMed, 249 citations in OpenAlex.
- Multiple Eurasian Origins and Admixture Shaped the Genomic Legacy of the House Mouse Invasion in Africa.Molecular ecology · 2026Article
- Anapc5 and Anapc7 as genetic modifiers of KIF18A function in fertility and mitotic progression.Scientific reports · 2025Article
- Genetic structure and demographic history of house mice in western Europe inferred using whole-genome sequences.Proceedings. Biological sciences · 2025Article
- Purifying Selection Influences the Comparison of Heterozygosities between Populations.Biology · 2024Article
- Across two continents: The genomic basis of environmental adaptation in house mice (Mus musculus domesticus) from the Americas.PLoS genetics · 2024Article
- Do genetic loci that cause reproductive isolation in the lab inhibit gene flow in nature?Evolution; international journal of organic evolution · 2024Article
- Insertion-Deletion Events Are Depleted in Protein Regions with Predicted Secondary Structure.Genome biology and evolution · 2024Article
- Inference of selective forces on house mouse genomes during secondary contact in East Asia.Genome research · 2024Article
- The Expansion of House Mouse Major Urinary Protein Genes Likely Did Not Facilitate Commensalism with Humans.Genes · 2023Article
- Across two continents: the genomic basis of environmental adaptation in house mice (bioRxiv : the preprint server for biology · 2023Article
- Meiotic Recognition of Evolutionarily Diverged Homologs: Chromosomal Hybrid Sterility Revisited.Molecular biology and evolution · 2023Article
- The demographic history of house mice (Mus musculus domesticus) in eastern North America.G3 (Bethesda, Md.) · 2023Article
- Rapid Evolution of the Fine-scale Recombination Landscape in Wild House Mouse (Mus musculus) Populations.Molecular biology and evolution · 2023Article
- House mouse subspecies do differ in their social structure.Ecology and evolution · 2022Article
- Population structure and inbreeding in wild house mice (Mus musculus) at different geographic scales.Heredity · 2022Article
- Genic and chromosomal components of Prdm9-driven hybrid male sterility in mice (Mus musculus).Genetics · 2022Article
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- Insights into Mus musculus Population Structure across Eurasia Revealed by Whole-Genome Analysis.Genome biology and evolution · 2022Article
- Shifting focus from resistance to disease tolerance: A review on hybrid house mice.Ecology and evolution · 2022Review
56 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 5 countries.
Funding
Abstract
Patterns of genetic differentiation among taxa at early stages of divergence provide an opportunity to make inferences about the history of speciation. Here, we conduct a survey of DNA-sequence polymorphism and divergence at loci on the autosomes, X chromosome, Y chromosome and mitochondrial DNA in samples of Mus domesticus, M. musculus and M. castaneus. We analyzed our data under a divergence with gene flow model and estimate that the effective population size of M. castaneus is 200,000-400,000, of M. domesticus is 100,000-200,000 and of M. musculus is 60,000-120,000. These data also suggest that these species started to diverge approximately 500,000 years ago. Consistent with this recent divergence, we observed considerable variation in the genealogical patterns among loci. For some loci, all alleles within each species formed a monophyletic group, while at other loci, species were intermingled on the phylogeny of alleles. This intermingling probably reflects both incomplete lineage sorting and gene flow after divergence. Likelihood ratio tests rejected a strict allopatric model with no gene flow in comparisons between each pair of species. Gene flow was asymmetric: no gene flow was detected into M. domesticus, while significant gene flow was detected into both M. castaneus and M. musculus. Finally, most of the gene flow occurred at autosomal loci, resulting in a significantly higher ratio of fixed differences to polymorphisms at the X and Y chromosomes relative to autosomes in some comparisons, or just the X chromosome in others, emphasizing the important role of the sex chromosomes in general and the X chromosome in particular in speciation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.