ArticleBiological cybernetics1991
Linear systems analysis of the relationship between firing of deep cerebellar neurons and the classically conditioned nictitating membrane response in rabbits.
Article in Biological cybernetics, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 22 citations in OpenAlex.
- An agonist-antagonist cerebellar nuclear system controlling eyelid kinematics during motor learning.Frontiers in neuroanatomy · 2012Article
- Dynamic changes in the cerebellar-interpositus/red-nucleus-motoneuron pathway during motor learning.Cerebellum (London, England) · 2011Article
- Neural circuitry and plasticity mechanisms underlying delay eyeblink conditioning.Learning & memory (Cold Spring Harbor, N.Y.) · 2011Review
- Identification of physiological systems: a robust method for non-parametric impulse response estimation.Medical & biological engineering & computing · 1997Article
- Control of rabbit nictitating membrane movements. II. Analysis of the relation of motoneuron activity to behavior.Biological cybernetics · 1992Article
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
The correlation of the activity of neurons in the interposed and dentate nuclei of the cerebellum with conditioned movements of the nictitating membrane was investigated using linear systems analysis. The activity of single deep cerebellar nuclear cells was assumed to be the input to a linear system that produced nictitating membrane movement. Data were initially analyzed with a causal model to assess the degree to which past neural activity predicted the conditioned response. 55 of 165 cells had correlation coefficients of 0.50 or greater between the model's moment-to-moment output and the actual output, with two interpositus cells having correlation coefficients of greater than 0.90. Double-sided impulse responses indicated that afference from the face and efference copy probably affect deep cerebellar neural activity. Nonlinearities were also found in the relationship between neuronal activity and conditioned movement. It was concluded that cerebellar deep nuclear firing is highly correlated with future nictitating membrane movements but that the firing-movement relationship contains noncausal and nonlinear components.
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Registered trials
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