ReviewInternational journal of biological sciences2009
BRCA1, hormone, and tissue-specific tumor suppression.
Review in International journal of biological sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Transcription factor BRCA1 is associated with BMPR1B transcriptional activity in sheep ovarian granulosa cells.Frontiers in veterinary science · 2025Article
- Prioritizing and characterizing functionally relevant genes across human tissues.PLoS computational biology · 2021Article
- MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors.Nature communications · 2019Article
- BRCA1 Attenuates Progesterone Effects on Proliferation and NFκB Activation in Normal Human Mammary Epithelial Cells.Journal of mammary gland biology and neoplasia · 2019Article
- BRCA1-associated R-loop affects transcription and differentiation in breast luminal epithelial cells.Nucleic acids research · 2019Article
- BRCA1 and Breast Cancer: a Review of the Underlying Mechanisms Resulting in the Tissue-Specific Tumorigenesis in Mutation Carriers.Journal of breast cancer · 2019Review
- BRCA1-Dependent Transcriptional Regulation: Implication in Tissue-Specific Tumor Suppression.Cancers · 2018Review
- hsa-miR-212 modulates the radiosensitivity of glioma cells by targeting BRCA1.Oncology reports · 2018Article
- Article
- RANKL/RANK: from bone loss to the prevention of breast cancer.Open biology · 2016Review
- Article
- Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells.Breast cancer research : BCR · 2014Article
- Tissue-specific tumor suppression by BRCA1.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Circulating estrogens and estrogens within the breast among postmenopausal BRCA1/2 mutation carriers.Breast cancer research and treatment · 2014Article
- Plant hormone signaling and modulation of DNA repair under stressful conditions.Plant cell reports · 2013Review
- Assessing estrogen signaling aberrations in breast cancer risk using genetically engineered mouse models.Annals of the New York Academy of Sciences · 2011Review
- BRCA1/BARD1 complex interacts with steroidogenic factor 1--A potential mechanism for regulation of aromatase expression by BRCA1.The Journal of steroid biochemistry and molecular biology · 2011Article
- Biosensors: the new wave in cancer diagnosis.Nanotechnology, science and applications · 2010Review
- Mouse models of inherited cancer syndromes.Hematology/oncology clinics of North America · 2010Review
- BRCA1 affects global DNA methylation through regulation of DNMT1.Cell research · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Germline mutations of BRCA1 predispose women to breast and ovarian cancers. Elucidating molecular mechanism of tissue- and gender-specific phenomena in BRCA1-related tumors is a key to our understanding of BRCA1 function in tumor suppression. This review summarizes studies in recent years on the link between BRCA1 and estrogen/progesterone signaling pathways, as well as discusses various models underscoring a triangle relationship among BRCA1, estrogen and genome instability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.