Evidence map›Paper›PMID 19118566›Full record

ReviewSteroids2009

Integrated actions of progesterone receptor and cell cycle machinery regulate breast cancer cell proliferation.

Gwen E Dressing, Carol A Lange

Open access · greenAbstract readReview
In one paragraph

Review in Steroids, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  7. Review
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  13. Review
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  17. Review
  18. Article
  19. Postmenopausal hormone therapy: an Endocrine Society scientific statement.The Journal of clinical endocrinology and metabolism · 2010
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gwen E DressingDepartment of Medicine, Division of Hematology, Oncology, and Transplantation, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, United States.
Carol A Lange
University of Minnesota Medical Center · US

Funding

TRAINING GRANT IN MICROBIOLOGY/CANCER RESEARCHT32CA009138 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Scott M. Dehm · 1985 to 2026
$11.3M
Progestin and growth factor cross-talk in breast cancerR01CA123763 · NCI · UNIVERSITY OF MINNESOTA · PI LANGE, CAROL A · 2006 to 2010
$1.1M
PROGESTIN AND GROWTH FACTOR CROSS-TALK IN BREAST CANCERR01DK053825 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LANGE, CAROL ANN · 1997 to 2004
$975k
NCI NIH HHS R01 CA123763NCI NIH HHS T32 CA009138NIDDK NIH HHS R01 DK053825
6 · The paper itself

Abstract

Multiple laboratories have investigated progesterone receptor (PR) involvement in breast cancer cell cycle progression. There is now a growing body of evidence demonstrating complex interactions between PR and cell cycle regulatory proteins. Here we review the current literature linking PR to cell cycle control and discuss gaps in the current knowledge. A more complete understanding of the relationships between PR and cell cycle regulatory molecules may reveal additional avenues for prevention and treatment of steroid receptor positive breast cancers.

Indexed as

Cell ProliferationAnimalsBreast NeoplasmsCell CycleHumansReceptors, ProgesteroneSignal TransductionReceptors, Progesterone

Identifiers

PMID19118566
PMCPMC4871707
OpenAlexW2053508270

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.