ArticleBMC musculoskeletal disorders2009
Bone mass in schizophrenia and normal populations across different decades of life.
Article in BMC musculoskeletal disorders, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- The neglected association between schizophrenia and bone fragility: a systematic review and meta-analyses.Translational psychiatry · 2024Pooled it
- Lower Bone Mineral Density at the Hip and Lumbar Spine in People with Psychosis Versus Controls: a Comprehensive Review and Skeletal Site-Specific Meta-analysis.Current osteoporosis reports · 2016Pooled it
- Bone Mineral Density in Schizophrenia: An Update of Current Meta-Analysis and Literature Review Under Guideline of PRISMA.Medicine · 2015Pooled it
- [Subgroup-specific therapy of low back pain: description and validity of two classification systems].Der Orthopade · 2013Pooled it
- Treatment of Comorbid Schizophrenia in an Adolescent with Osteogenesis Imperfecta: A Case Report.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2026Article
- Risk factors for osteoporosis in chronic schizophrenia on long-term treatment with antipsychotics: a cross-sectional study.BMC psychiatry · 2023Article
- Antipsychotic medication use in association with quantitative heel ultrasound (QUS).Bone reports · 2023Article
- Dopamine, Immunity, and Disease.Pharmacological reviews · 2023Review
- Hip, vertebral, and wrist fracture risks and schizophrenia: a nationwide longitudinal study.BMC psychiatry · 2022Article
- Peri- and Post-Menopausal Women with Schizophrenia and Related Disorders Are a Population with Specific Needs: A Narrative Review of Current Theories.Journal of personalized medicine · 2021Review
- Long-term Use of Clozapine is Protective for Bone Density in Patients with Schizophrenia.Scientific reports · 2019Article
- Effect of risperidone on proliferation and apoptosis of MC3T3-E1 cells.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Article
- Management of common adverse effects of antipsychotic medications.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018Article
- Effects of Antipsychotics on Bone Mineral Density in Patients with Schizophrenia: Gender Differences.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2016Review
- Chronic Psychosocial Stress Impairs Bone Homeostasis: A Study in the Social Isolation Reared Rat.Frontiers in pharmacology · 2016Article
- A Role for the Transcription Factor Nk2 Homeobox 1 in Schizophrenia: Convergent Evidence from Animal and Human Studies.Frontiers in behavioral neuroscience · 2016Article
- Factors associated with decreased bone mineral density in postmenopausal women with schizophrenia.Clinical interventions in aging · 2016Article
- Accelerated aging in schizophrenia patients: the potential role of oxidative stress.Aging and disease · 2014Review
- Randomized controlled trial comparing changes in serum prolactin and weight among female patients with first-episode schizophrenia over 12 months of treatment with risperidone or quetiapine.Shanghai archives of psychiatry · 2014Article
- Osteoporosis associated with antipsychotic treatment in schizophrenia.International journal of endocrinology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic schizophrenic patients have been reported as having higher osteoporosis prevalence. Survey the bone mass among schizophrenic patients and compare with that of the local community population and reported data of the same country to figure out the distribution of bone mass among schizophrenic patients.
methods965 schizophrenic patients aged 20 years and over in Yuli Veterans Hospital and 405 members aged 20 and over of the community living in the same town as the institute received bone mass examination by a heel qualitative ultrasound (QUS) device. Bone mass distribution was stratified to analyzed and compared with community population.
resultsSchizophrenic patients have lower bone mass while they are young. But aging effect on bone mass cannot be seen. Accelerated bone mass loss during menopausal transition was not observed in the female schizophrenic patients as in the subjects of the community female population.
conclusionSchizophrenic patients have lower bone mass than community population since they are young. Further study to investigate the pathophysiological process is necessary to delay or avoid the lower bone mass in schizophrenia patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.