Evidence map›Paper›PMID 19118341›Full record

ReviewMicrobiology (Reading, England)2009

Early molecular-recognition events in the synthesis and export of group 2 capsular polysaccharides.

Eric R Vimr, Susan M Steenbergen

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology (Reading, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. KpsC and KpsS are retaining 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferases involved in synthesis of bacterial capsules.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  7. Article
  8. Article
  9. Campylobacter polysaccharide capsules: virulence and vaccines.Frontiers in cellular and infection microbiology · 2012
    Review
  10. Article
  11. ABC transporters involved in export of cell surface glycoconjugates.Microbiology and molecular biology reviews : MMBR · 2010
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eric R VimrLaboratory of Sialobiology, Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Susan M SteenbergenLaboratory of Sialobiology, Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
University of Illinois Urbana-Champaign · US

Funding

Regulation of the Poly Sialic Virulence FactorR01AI042015 · NIAID · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI VIMR, ERIC ROSS · 1998 to 2014
$2.6M
Regulation of the Poly Sialic Virulence FactorR56AI042015 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI VIMR, ERIC ROSS · 2009 to 2009
$238k
NIAID NIH HHS AI042015NIAID NIH HHS R01 AI042015NIAID NIH HHS R56 AI042015
6 · The paper itself

Abstract

The outer membrane (OM) of almost all Gram-negative bacteria is composed of phospholipids, lipopolysaccharide, proteins and capsular or loosely adherent polysaccharides that together mediate cellular interactions with diverse environments. Most OM components are synthesized intracellularly or at the inner membrane (IM) and thus require an export mechanism. This mini-review focuses on recent progress in understanding how synthesis of one kind of capsular polysaccharide (group 2) is coupled to the export apparatus located in the IM and spanning the periplasmic space, thus providing a transport channel to the cell surface. Although the model system for these investigations is the medically important extraintestinal pathogen Escherichia coli K1 and its polysialic acid capsule, the conclusions are general for other group 2 and group 2-like polysaccharides synthesized by many different bacterial species.

Indexed as

Biological TransportGene Expression Regulation, BacterialBacterial CapsulesCell MembraneEscherichia coliEscherichia coli ProteinsEscherichia coli Proteins

Identifiers

PMID19118341
PMCPMC4044924
OpenAlexW2096880511

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.