The many causes of severe congenital neutropenia.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).PLoS genetics · 2011
   Pooled it
2. Interactions of the CSF3R polymorphism and early stress on future orientation: evidence for the differential model of stress-related growth.Epidemiology and psychiatric sciences · 2024
   Article
3. Evaluation of Neutrophil Elastase Inhibitors as Potential Therapies forJournal of cellular immunology · 2024
   Article
4. Pediatric Bone Marrow Failure: A Broad Landscape in Need of Personalized Management.Journal of clinical medicine · 2023
   Review
5. Mutant allele knockout with novel CRISPR nuclease promotes myelopoiesis in ELANE neutropenia.Molecular therapy. Methods & clinical development · 2022
   Article
6. Co-Occurring CSF3R W791* Germline and Somatic T618I Driver Mutations Induce Early CNL and Clonal Progression to Mixed Phenotype Acute Leukemia.Current oncology (Toronto, Ont.) · 2022
   Article
7. Comparison of Gene Editing versus a Neutrophil Elastase Inhibitor as Potential Therapies forJournal of cellular immunology · 2022
   Article
8. Registries for study of nonmalignant hematological diseases: the example of the Severe Chronic Neutropenia International Registry.Current opinion in hematology · 2020
   Observational
9. Neutropenia in the age of genetic testing: Advances and challenges.American journal of hematology · 2019
   Review
10. Description of anJournal of pediatric genetics · 2019
    Article
11. Ultra-SensitiveFrontiers in immunology · 2019
    Article
12. Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive.The Journal of clinical investigation · 2018
    Article
13. Identification of novelCold Spring Harbor molecular case studies · 2018
    Review
14. Chronic neutrophilic leukemia: new science and new diagnostic criteria.Blood cancer journal · 2018
    Review
15. Elastase inhibitors as potential therapies forJournal of leukocyte biology · 2017
    Article
16. Association Between Absolute Neutrophil Count and Variation at TCIRG1: The NHLBI Exome Sequencing Project.Genetic epidemiology · 2016
    Article
17. Use of granulocyte colony-stimulating factor during pregnancy in women with chronic neutropenia.Obstetrics and gynecology · 2015
    Observational
18. Severe congenital neutropenia and chronic neutrophilic leukemia: an intriguing molecular connection unveiled by oncogenic mutations in CSF3R.Haematologica · 2013
    Article
19. Survival and differentiation defects contribute to neutropenia in glucose-6-phosphatase-β (G6PC3) deficiency in a model of mouse neutrophil granulocyte differentiation.Cell death and differentiation · 2013
    Article
20. Prevalence of a new auto-activating colony stimulating factor 3 receptor mutation (CSF3R-T595I) in acute myeloid leukemia and severe congenital neutropenia.Haematologica · 2013
    Article

Corrections and comments

• Comment on
  A syndrome with congenital neutropenia and mutations in G6PC3.2009

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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