ArticleJournal of bacteriology2009
T-POP array identifies EcnR and PefI-SrgD as novel regulators of flagellar gene expression.
Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 55 citations in OpenAlex.
- A Small RNA Derived From the 5' End of the IS200 tnpA Transcript Regulates Multiple Virulence Regulons in Salmonella typhimurium.Molecular microbiology · 2025Article
- Role of the LuxR solo, SdiA, in eavesdropping on foreign bacteria.FEMS microbiology reviews · 2025Review
- A mathematical model of flagellar gene regulation and construction in Salmonella enterica.PLoS computational biology · 2020Article
- A Family of Small Intrinsically Disordered Proteins Involved in Flagellum-Dependent Motility in Salmonella enterica.Journal of bacteriology · 2019Article
- Article
- Growth rate control of flagellar assembly in Escherichia coli strain RP437.Scientific reports · 2017Article
- An Updated View on the Rck Invasin ofFrontiers in cellular and infection microbiology · 2017Review
- Flagella-independent surface motility in Salmonella enterica serovar Typhimurium.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Regulatory principles governing Salmonella and Yersinia virulence.Frontiers in microbiology · 2015Review
- Characterization of Novel Factors Involved in Swimming and Swarming Motility in Salmonella enterica Serovar Typhimurium.PloS one · 2015Article
- Mutually repressing repressor functions and multi-layered cellular heterogeneity regulate the bistable Salmonella fliC census.Molecular microbiology · 2014Article
- Analysis of factors that affect FlgM-dependent type III secretion for protein purification with Salmonella enterica serovar Typhimurium.Journal of bacteriology · 2014Article
- The Salmonella Spi1 virulence regulatory protein HilD directly activates transcription of the flagellar master operon flhDC.Journal of bacteriology · 2014Article
- The effect of cell growth phase on the regulatory cross-talk between flagellar and Spi1 virulence gene expression.PLoS pathogens · 2014Article
- RflM functions as a transcriptional repressor in the autogenous control of the Salmonella Flagellar master operon flhDC.Journal of bacteriology · 2013Article
- The multifunctional protein YdiV represses P fimbria-mediated adherence in uropathogenic Escherichia coli.Journal of bacteriology · 2013Article
- FlgM as a secretion moiety for the development of an inducible type III secretion system.PloS one · 2013Article
- Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility.Nucleic acids research · 2012Article
- Article
- Non-genetic diversity shapes infectious capacity and host resistance.Trends in microbiology · 2012Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The T-POP transposon was employed in a general screen for tetracycline (Tet)-induced chromosomal loci that exhibited Tet-activated or Tet-repressed expression of a fliC-lac transcriptional fusion. Insertions that activated flagellar transcription were located in flagellar genes. T-POP insertions that exhibited Tet-dependent fliC-lac inhibition were isolated upstream of the ecnR, fimZ, pefI-srgD, rcsB, and ydiV genes and in the flagellar gene flgA, which is located upstream of the anti-sigma(28) factor gene flgM. When expressed from the chromosomal P(araBAD) promoter, EcnR, FimZ, PefI-SrgD, and RcsB inhibited the transcription of the flagellar class 1 flhDC operon. YdiV, which is weakly homologous to EAL domain proteins involved in cyclic-di-GMP regulation, appears to act at a step after class 1 transcription. By using a series of deletions of the regulatory genes to try to disrupt each pathway, these regulators were found to act largely independently of one another. These results identify EcnR and PefI-SrgD as additional components of the complex regulatory network controlling flagellar expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.