Evidence map›Paper›PMID 19114009›Full record

ArticleRetrovirology2008

MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals.

Laurent Houzet, Man Lung Yeung, Valery de Lame, Dhara Desai, Stephen M Smith, Kuan-Teh Jeang

Abstract read
In one paragraph

Article in Retrovirology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

123 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. MiRNA: Biological Regulator in Host-Parasite Interaction during Malaria Infection.International journal of environmental research and public health · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. The role of miR-29 family in disease.Journal of cellular biochemistry · 2021
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review

63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laurent HouzetMolecular Virology Section, Laboratory of Molecular Microbiology National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA. houzetl@niaid.nih.gov
Man Lung Yeung
Valery de Lame
Dhara Desai
Stephen M Smith
Kuan-Teh Jeang

Funding

Molecular Mechanisms Of Human Immunodeficiency Virus Trans-regulatory ProteinsZIAAI000547 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI JEANG, KUAN-TEH · 2009 to 2013
$5.9M
MOLECULAR MECHANISMS OF HUMAN RETROVIRUS TRANS-REGULATORY PROTEINSZ01AI000547 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI JEANG, KUAN-TEH · 1989 to 2008
$2.8M
Intramural NIH HHS
6 · The paper itself

Abstract

MicroRNAs (miRNAs) play diverse roles in regulating cellular and developmental functions. We have profiled the miRNA expression in peripheral blood mononuclear cells from 36 HIV-1 seropositive individuals and 12 normal controls. The HIV-1-positive individuals were categorized operationally into four classes based on their CD4+ T-cell counts and their viral loads. We report that specific miRNA signatures can be observed for each of the four classes.

Indexed as

HIV SeropositivityCohort StudiesGene Expression RegulationHIV-1HIV InfectionsHumansLeukocytes, MononuclearMicroRNAsT-LymphocytesMicroRNAs

Identifiers

PMID19114009
PMCPMC2644721

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.