ArticleJournal of gerontological nursing2008
Prevalence and treatment of neuropsychiatric symptoms in advanced dementia.
Article in Journal of gerontological nursing, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Optimal nonpharmacological management of agitation in Alzheimer's disease: challenges and solutions.Clinical interventions in aging · 2016Pooled it
- Needs of people with dementia in long-term care: a systematic review.American journal of Alzheimer's disease and other dementias · 2013Pooled it
- Triggered Palliative Care for Late-Stage Dementia: A Pilot Randomized Trial.Journal of pain and symptom management · 2019Trial
- The implementation of the serial trial intervention for pain and challenging behaviour in advanced dementia patients (STA OP!): a clustered randomized controlled trial.BMC geriatrics · 2011Trial
- Emergency department use and responsiveness to the palliative care needs of patients with dementia at the end of life: A scoping review.Palliative & supportive care · 2025Article
- Future Therapeutic Strategies for Alzheimer's Disease: Focus on Behavioral and Psychological Symptoms.International journal of molecular sciences · 2024Review
- Essential New Complexity-Based Themes for Patient-Centered Diagnosis and Treatment of Dementia and Predementia in Older People: Multimorbidity and Multilevel Phenomenology.Journal of clinical medicine · 2024Review
- Comfort First: Development and pilot testing of a web-based video training to disseminate Comfort Matters dementia care.Journal of the American Geriatrics Society · 2023Article
- Dementia Care in the Last Year of Life: Experiences in a Community Practice and in Skilled Nursing Facilities.Journal of palliative care · 2023Article
- Understanding neuropsychiatric symptoms in Alzheimer's disease: challenges and advances in diagnosis and treatment.Frontiers in neuroscience · 2023Review
- Impact of agitation in long-term care residents with dementia in the United States.International journal of geriatric psychiatry · 2021Article
- Nursing Home Transfers for Behavioral Concerns: Findings from the OPTIMISTIC Demonstration Project.Journal of the American Geriatrics Society · 2021Article
- Selecting Outcomes to Ensure Pragmatic Trials Are Relevant to People Living with Dementia.Journal of the American Geriatrics Society · 2020Article
- Real-World Treatment Patterns and Characteristics Among Patients with Agitation and Dementia in the United States: Findings from a Large, Observational, Retrospective Chart Review.Journal of Alzheimer's disease : JAD · 2020Observational
- Institutionalization risk and costs associated with agitation in Alzheimer's disease.Alzheimer's & dementia (New York, N. Y.) · 2019Article
- Psychiatric Aspects of Dementia.Continuum (Minneapolis, Minn.) · 2016Article
- Severe Impairment Rating Scale: A Useful and Brief Cognitive Assessment Tool for Advanced Dementia for Nursing Home Residents.American journal of Alzheimer's disease and other dementias · 2016Article
- Predictors of progression to severe Alzheimer's disease in an incidence sample.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2013Article
- Drug therapy optimization at the end of life.Drugs & aging · 2012Review
- The effect of comorbidity burden on health care utilization for patients with cancer using hospice.Journal of palliative medicine · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Neuropsychiatric symptoms (NPS) are common in dementia, although little is known about their prevalence and treatment near the end of life. This study used a retrospective review of the medical records of 123 hospice-eligible nursing home residents with advanced dementia to investigate the prevalence of NPS and NPS-targeted pharmacological and non-pharmacological treatments. The most prevalent NPS were agitation or aggression (50.4%), depression (45.5%), and withdrawal/lethargy (43.1%). Of the 105 (85.4%) residents who exhibited one or more NPS, 90.5% were receiving at least one NPS-targeted treatment, yet 41.9% received no documented nonpharmacological NPS-targeted care. The majority of documented nonpharmacological care focused on safety and explanations or instructions given to residents. Given the high prevalence of comorbidities, associated risks for medication interactions or serious side effects, and potential low-risk benefits of psychobehavioral care, these findings raise concerns about how to best increase the provision and documentation of nonpharmacological care in advanced dementia.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.