ArticleBrain imaging and behavior2008
Occipital-temporal Reduction and Sustained Visual Attention Deficit in Prenatal Alcohol Exposed Adults.
Article in Brain imaging and behavior, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Persistent dose-dependent changes in brain structure in young adults with low-to-moderate alcohol exposure in utero.Alcoholism, clinical and experimental research · 2012Trial
- The Impact of a Neurocollaborative Theraplay® Informed Intervention on the Presentations of Developmental Trauma and Attachment Difficulties in Adopted Children with Prenatal Alcohol Exposure: An Extended Case Study.Journal of child & adolescent trauma · 2025Article
- Alcohol Toxicity in the Developing Cerebellum.Diagnostics (Basel, Switzerland) · 2024Article
- Examining the effects of prenatal alcohol exposure on performance of the sustained attention to response task in children with an FASD.Human brain mapping · 2023Article
- The interaction of genetic sex and prenatal alcohol exposure on health across the lifespan.Frontiers in neuroendocrinology · 2023Review
- Distance-based functional criticality in the human brain: intelligence and emotional intelligence.BMC bioinformatics · 2021Article
- Effects of alfaxalone on cerebral blood flow and intrinsic neural activity of rhesus monkeys: A comparison study with ketamine.Magnetic resonance imaging · 2021Article
- Covariation Between Brain Function (MEG) and Structure (DTI) Differentiates Adolescents with Fetal Alcohol Spectrum Disorder from Typically Developing Controls.Neuroscience · 2020Article
- Fetal Alcohol Spectrum Disorders: A Review of the Neurobehavioral Deficits Associated With Prenatal Alcohol Exposure.Alcoholism, clinical and experimental research · 2019Review
- Effects of Early Alcohol Exposure on Functional Organization and Microstructure of a Visual-Tactile Integrative Circuit.Alcoholism, clinical and experimental research · 2018Article
- Evaluation of prolonged administration of isoflurane on cerebral blood flow and default mode network in macaque monkeys anesthetized with different maintenance doses.Neuroscience letters · 2018Article
- Preliminary Findings that a Targeted Intervention Leads to Altered Brain Function in Children with Fetal Alcohol Spectrum Disorder.Brain sciences · 2017Article
- Effects of Long-Duration Administration of 1% Isoflurane on Resting Cerebral Blood Flow and Default Mode Network in Macaque Monkeys.Brain connectivity · 2017Article
- Differentiating the Effects of Familial Risk for Alcohol Dependence and Prenatal Exposure to Alcohol on Offspring Brain Morphology.Alcoholism, clinical and experimental research · 2017Article
- Prenatal Alcohol Exposure is Associated with Regionally Thinner Cortex During the Preadolescent Period.Cerebral cortex (New York, N.Y. : 1991) · 2016Article
- Developmental Trajectories for Visuo-Spatial Attention are Altered by Prenatal Alcohol Exposure: A Longitudinal FMRI Study.Cerebral cortex (New York, N.Y. : 1991) · 2015Article
- Visual search for feature conjunctions: an fMRI study comparing alcohol-related neurodevelopmental disorder (ARND) to ADHD.Journal of neurodevelopmental disorders · 2015Article
- A study of cortical morphology in children with fetal alcohol spectrum disorders.Human brain mapping · 2014Article
- Cortical morphology in children with alcohol-related neurodevelopmental disorder.Brain and behavior · 2014Article
- Connectomics signatures of prenatal cocaine exposure affected adolescent brains.Human brain mapping · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Visual attention problems have been reported in association with prenatal alcohol exposure (PAE). With related behavioral data documented in literature, further investigation of this PAE effect would benefit from integrating functional and anatomical imaging data to ascertain its neurobiological basis. The current study investigated the possible functional and anatomical bases for the PAE-related visual sustained attention deficit. Functional magnetic resonance imaging (fMRI) data were collected while the subjects performed a sustained visual attention task. High resolution, three dimensional anatomical images were also collected for morphometric evaluation. In the alcohol-affected subjects, we observed a significant white and gray matter volume reduction in the occipital-temporal area. Meanwhile, their fMRI activations in the same region resided more superiorly than that of the controls resulting in reduced activation in the ventral occipital-temporal area. The location of this PAE functional abnormality approximately matches that of the significant structural reduction. In addition to the well documented corpus callosum abnormalities observed in PAE subjects, the present results reveal a teratogenic effect on the occipital-temporal area. Furthermore, as the occipital-temporal area plays an important role in visual attention, the current observation suggests a neurobiological underpinning for the PAE related deficit in sustained visual attention.
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Registered trials
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