Evidence map›Paper›PMID 19111440›Full record

ReviewJournal of voice : official journal of the Voice Foundation2009

Vocal fold surface hydration: a review.

Ciara Leydon, Mahalakshmi Sivasankar, Danielle Lodewyck Falciglia, Christopher Atkins, Kimberly V Fisher

Abstract readReview
In one paragraph

Review in Journal of voice : official journal of the Voice Foundation, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 100 citations in OpenAlex.

  1. Article
  2. Prevalence and risk factors of voice disorders among tour guides in Cappadocia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Mechanotransduction in the Vocal Fold Microenvironment: A Narrative Review.Journal of speech, language, and hearing research : JSLHR · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Hydration State and Hyaluronidase Treatment Significantly Affect Porcine Vocal Fold Biomechanics.Journal of voice : official journal of the Voice Foundation · 2023
    Article
  9. Article
  10. Article
  11. The sounds of prehistoric speech.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Sensory Innervation of the Larynx and the Search for Mucosal Mechanoreceptors.Journal of speech, language, and hearing research : JSLHR · 2021
    Article
  16. Article
  17. Article
  18. A Computational Study of Vocal Fold Dehydration During Phonation.IEEE transactions on bio-medical engineering · 2017
    Article
  19. Article
  20. Languages in Drier Climates Use Fewer Vowels.Frontiers in psychology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ciara LeydonDepartment of Speech Communication Arts and Sciences, Brooklyn College of The City University of New York, New York 12110, USA. cleydon@brooklyn.cuny.edu
Mahalakshmi Sivasankar
Danielle Lodewyck Falciglia
Christopher Atkins
Kimberly V Fisher
Northwestern University · USBrooklyn College · USNew York University · US

Funding

Laryngeal hydration aerosol for prevention of voice disordersR01DC007932 · NIDCD · NORTHWESTERN UNIVERSITY · PI FISHER, KIMBERLY V · 2006 to 2007
$994k
COMPUTATIONAL MODELS OF LANGUAGE DISORDERSK08DC000068 · NIDCD · CARNEGIE-MELLON UNIVERSITY · PI EVANS, JULIA L · 1993 to 1997
–
NIDCD NIH HHS K08-DC0068NIDCD NIH HHS R01 DC007932
6 · The paper itself

Abstract

Vocal fold surface liquid homeostasis contributes to optimal vocal physiology. In this paper we review emerging evidence that vocal fold surface liquid is maintained in part by salt and water fluxes across the epithelium. Based on recent immunolocalization and electrophysiological findings, we describe a transcellular pathway as one mechanism for regulating superficial vocal fold hydration. We propose that the pathway includes the sodium-potassium pump, sodium-potassium-chloride cotransporter, epithelial sodium channels, cystic fibrosis transmembrane regulator chloride channels, and aquaporin water channels. By integrating knowledge of the regulating mechanisms underlying ion and fluid transport with observations from hydration challenges and treatments using in vitro and in vivo studies, we provide a theoretical basis for understanding how environmental and behavioral challenges and clinical interventions may modify vocal fold surface liquid composition. We present converging evidence that clinical protocols directed at facilitating vocal fold epithelial ion and fluid transport may benefit healthy speakers, those with voice disorders, and those at risk for voice disorders.

Indexed as

AnimalsHumansIon TransportLaryngeal MucosaVocal CordsVoiceWaterWater

Identifiers

PMID19111440
PMCPMC2810851
OpenAlexW2012636123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.