ArticleJournal of the National Medical Association2008
Sociodemographic factors predict early discontinuation of HIV non-nucleoside reverse transcriptase inhibitors and protease inhibitors.
Article in Journal of the National Medical Association, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Factors related to loss to follow-up among people living with HIV: a systematic review.Revista do Instituto de Medicina Tropical de Sao Paulo · 2025Pooled it
- Factors associated with loss to follow-up among people living with HIV at public health facilities in Manaus, Brazil: a multicentric study.BMC public health · 2025Article
- Nevirapine and tuberculosis predict first-line treatment failure in HIV patients in Indonesia: Case-control study.Annals of medicine and surgery (2012) · 2020Article
- Treatment Adherence And Persistence Among HIV-1 Patients Newly Starting Treatment.Patient preference and adherence · 2019Article
- Sources of racial/ethnic differences in awareness of HIV vaccine trials.American journal of public health · 2014Article
- Cultural rationales guiding medication adherence among African American with HIV/AIDS.AIDS patient care and STDs · 2011Article
- Underutilization of the AIDS Drug Assistance Program: associated factors and policy implications.Health services research · 2011Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND/
objectiveHIV infection has a devastating impact on individual and public health, and affects populations disproportionately. Treatment with antiretroviral therapy (ART) saves lives, but long-term adherence to ART is critical to its success. We performed an observational cohort study to determine the influence of race, sex and other sociodemographic factors on early ART discontinuations among HIV-infected persons.
methodsTennCare-enrolled adults of black or white non-Hispanic race beginning ART with either a non-nucleoside reverse transcriptase inhibitor (NNRTI) or protease inhibitor (PI) between 1996-2003 (N=3654) were assessed for early discontinuation. A subgroup of discontinuations was validated using the primary medical record.
resultsBlacks were more likely than whites to discontinue NNRTIs (37 vs. 28%; P=0.003) and PIs (36 vs. 25%; P < or = 0.001). In multivariable models adjusting for race, sex, age, early HIV-related medical encounter, urban residence and TennCare enrollment category, black race, female sex and younger age were independent predictors of discontinuation among those starting PIs. Among persons starting NNRTIs, black race, younger age and a disability-based enrollment category predicted early drug discontinuation, but female sex did not.
conclusionsOur results suggest that sociodemographic factors were associated with early NNRTI and PI discontinuation in this population, and some factors were ART class specific.
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Registered trials
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