Evidence map›Paper›PMID 19110486›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2009

Stem cell therapy for Alport syndrome: the hope beyond the hype.

Oliver Gross, Dorin-Bogdan Borza, Hans-Joachim Anders, Christoph Licht, Manfred Weber, Stephan Segerer, Roser Torra, Marie-Claire Gubler, Laurence Heidet, Scott Harvey and 12 more

Open access · bronzeAbstract read
In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Guideline
  2. Spectrum of Alport syndrome in an Indian cohort.Pediatric nephrology (Berlin, Germany) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. From Patient to Dish and Back Again: Are We There Yet?Journal of the American Society of Nephrology : JASN · 2015
    Article
  7. Article
  8. Article
  9. The regenerative potential of parietal epithelial cells in adult mice.Journal of the American Society of Nephrology : JASN · 2014
    Article
  10. Feasibility of repairing glomerular basement membrane defects in Alport syndrome.Journal of the American Society of Nephrology : JASN · 2014
    Article
  11. Danger control programs cause tissue injury and remodeling.International journal of molecular sciences · 2013
    Review
  12. Review
  13. Outcomes of male patients with Alport syndrome undergoing renal replacement therapy.Clinical journal of the American Society of Nephrology : CJASN · 2012
    Article
  14. Injection of amniotic fluid stem cells delays progression of renal fibrosis.Journal of the American Society of Nephrology : JASN · 2012
    Article
  15. Review
  16. Stem cell therapies benefit Alport syndrome.Journal of the American Society of Nephrology : JASN · 2009
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 17 institutions in 9 countries.

Oliver GrossDepartment of Nephrology and Rheumatology, University Hospital Gottingen, Gottingen, Germany. gross.oliver@med.uni-goettingen.de
Dorin-Bogdan Borza
Hans-Joachim Anders
Christoph Licht
Manfred Weber
Stephan Segerer
Roser Torra
Marie-Claire Gubler
Laurence Heidet
Scott Harvey
Dominic Cosgrove
George Lees
Clifford Kashtan
Martin Gregory
Judy Savige
Jie Ding
Paul Thorner
Dale R Abrahamson
Corinne Antignac
Karl Tryggvason
Billy Hudson
Jeffrey H Miner
Délégation Paris 5 · FRUniversity of Toronto · CAVanderbilt University Medical Center · USBoys Town National Research Hospital · USHôpital Necker-Enfants Malades · FRKarolinska Institutet · SEPeking University · CNPuigvert Foundation · ESTexas A&M University · USThe University of Melbourne · AUUniversitätsmedizin Göttingen · DEUniversity of Kansas Medical Center · USUniversity of Minnesota · USUniversity of Utah · USUniversity of Zurich · CHWashington University in St. Louis · USWitten/Herdecke University · DE

Funding

Molecular pathogenesis of anti-glomerular basement membrane nephritisR01DK080799 · NIDDK · VANDERBILT UNIVERSITY · PI BORZA, DORIN-BOGDAN · 2008 to 2012
$1.6M
NIDDK NIH HHS R01 DK080799
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Stem Cell TransplantationAnimalsAutoantigensCollagen Type IVHumansMiceNephritis, HereditaryRenal InsufficiencyAutoantigensCollagen Type IVtype IV collagen alpha3 chain

Identifiers

PMID19110486
PMCPMC3888105
OpenAlexW2153102493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.