ArticleJournal of clinical microbiology2009
Molecular epidemiology of norovirus gastroenteritis investigated using samples collected from children in Tunisia during a four-year period: detection of the norovirus variant GGII.4 Hunter as early as January 2003.
Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review.Virology journal · 2017Pooled it
- Article
- Epidemiological Evidence for Fecal-Oral Transmission of MurineFrontiers in public health · 2022Article
- Low Seroprevalence of Aichi Virus Infection in Taiwan.Pathogens (Basel, Switzerland) · 2021Article
- Preadaptation of pandemic GII.4 noroviruses in unsampled virus reservoirs years before emergence.Virus evolution · 2020Article
- Review
- Genetic and epidemiological analysis of norovirus from children with gastroenteritis in Botswana, 2013-2015.BMC infectious diseases · 2018Article
- Emerging recombinant noroviruses identified by clinical and waste water screening.Emerging microbes & infections · 2018Article
- Prevalence and Genetic Diversity of Enteric Viruses in Children with Diarrhea in Ouagadougou, Burkina Faso.PloS one · 2016Article
- Norovirus Epidemiology in Africa: A Review.PloS one · 2016Review
- Deciphering the Diversities of Astroviruses and Noroviruses in Wastewater Treatment Plant Effluents by a High-Throughput Sequencing Method.Applied and environmental microbiology · 2015Article
- Norovirus.Clinical microbiology reviews · 2015Review
- Etiology of Acute Diarrhea in Tunisian Children with Emphasis on Diarrheagenic Escherichia coli: Prevalence and Identification of E. coli Virulence Markers.Iranian journal of public health · 2014Article
- Rotavirus and norovirus infections among acute gastroenteritis children in Morocco.BMC infectious diseases · 2014Article
- Molecular detection of human noroviruses in influent and effluent samples from two biological sewage treatment plants in the region of Monastir, Tunisia.Food and environmental virology · 2014Article
- Norovirus-related chronic diarrhea in a patient treated with alemtuzumab for chronic lymphocytic leukemia.BMC infectious diseases · 2014Article
- Identification and characterization of antibody-binding epitopes on the norovirus GII.3 capsid.Journal of virology · 2014Article
- Norovirus genogroup II gastroenteritis in hospitalized children in South India.The American journal of tropical medicine and hygiene · 2013Article
- Detection and molecular characterisation of noroviruses in hospitalised children in Malawi, 1997-2007.Journal of medical virology · 2013Article
- The importance of intergenic recombination in norovirus GII.3 evolution.Journal of virology · 2013Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human noroviruses (NoVs) cause epidemic and endemic acute gastroenteritis in children and adults. To study the prevalence and genetic diversity of NoV in children in Tunisia, a total of 788 fecal samples were collected during a 4-year period in the region of Monastir, from children 12 years of age or younger, hospitalized or presenting in dispensaries with symptoms of acute gastroenteritis. NoV was detected by reverse transcription-PCR and confirmed by sequence analysis. This is the first report that describes the molecular epidemiology of NoV in Tunisian children: NoVs were characterized as the causative agent in 128 (16.2%) of the samples. Fourteen samples contained a mixture of two NoVs, and 33 samples were coinfected with additional enteric viruses. Eight distinct NoV genotypes were detected (GGI.2, GGI.4, GGII.1, GGII.4, GGII.8, GGII.14, GGIIb/GGII.2, and GGIIb/GGII.3). GGII.4 was the most prevalent genotype, accounting for 83 (64.8%) cases. Interestingly the GGII.4 variant Hunter, described as spreading all over the world in 2004, was found in Tunisia as early as January 2003. The delay of 1 year between the isolation in Tunisia and the worldwide emergence is somewhat surprising, considering the importance of the contacts between North Africa and Europe particularly. Nevertheless, this illustrates the idea that sporadic gastroenteritis cases may be a reservoir for emerging epidemic NoV strains.
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