ArticleInflammatory bowel diseases2009
Clinical features and outcome of patients with inflammatory bowel disease who use narcotics: a case-control study.
Article in Inflammatory bowel diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.
What it found
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Who cites it
41 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Varying patterns of risk factors for inflammatory bowel disease in the East and the West: insights from the global burden of disease study 2021.BMC public health · 2025Pooled it
- The Relationship Between Opioid Use and Healthcare Utilization in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.Inflammatory bowel diseases · 2022Pooled it
- A review of trial and real-world data applying elements of a realist approach to identify behavioural mechanisms supporting practitioners to taper opioids.British journal of clinical pharmacology · 2022Pooled it
- Efficacy of interventions to reduce long term opioid treatment for chronic non-cancer pain: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2022Pooled it
- Temporal Trends in and Associations With Nonsteroidal Anti-inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease.Arthritis care & research · 2026Article
- Moxibustion ameliorates chronic inflammatory visceral pain via spinal circRNA-miRNA-mRNA networks: a central mechanism study.Molecular brain · 2024Article
- Latent profiles of fatigue in inflammatory bowel disease.BMC gastroenterology · 2024Article
- Examining the influence of inflammatory bowel disease medications on sleep quality.JGH open : an open access journal of gastroenterology and hepatology · 2023Article
- Involvement of Intestinal Enteroendocrine Cells in Neurological and Psychiatric Disorders.Biomedicines · 2022Review
- Polysubstance use in inflammatory bowel disease.Journal of digestive diseases · 2021Article
- Article
- Opioid Use Associated With Higher Costs Among Patients With Inflammatory Bowel Disease.Crohn's & colitis 360 · 2021Article
- Preadmission Cannabis Use Is Positively Correlated With Inpatient Opioid Dose Exposure in Hospitalized Patients With Inflammatory Bowel Diseases.Inflammatory bowel diseases · 2021Article
- Predictors, rates, and trends of opioid use disorder among patients hospitalized with chronic pancreatitis.Annals of gastroenterology · 2021Article
- One-year risk of opioid use disorder after index hospitalization for inflammatory bowel disease.International journal of colorectal disease · 2020Article
- Pain in Inflammatory Bowel Disease Is Not Improved During Hospitalization: The Impact of Opioids on Pain and Healthcare Utilization.Digestive diseases and sciences · 2020Article
- Article
- Polypharmacy is a risk factor for disease flare in adult patients with ulcerative colitis: a retrospective cohort study.Intestinal research · 2019Article
- Experimental Colitis Enhances the Rate of Antinociceptive Tolerance to Morphine via Peripheral Opioid Receptors.The Journal of pharmacology and experimental therapeutics · 2019Article
- Focus on current and future management possibilities in inflammatory bowel disease-related chronic pain.International journal of colorectal disease · 2019Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe role of narcotic use in patients with inflammatory bowel disease (IBD) is poorly defined. We sought to determine the clinical features of patients with IBD who use narcotics and factors associated with the discontinuation of narcotics.
methodsA centralized index was used to identify 100 cases (patients with IBD receiving narcotics) and 100 matched controls evaluated in an IBD clinic between 1999 and 2002. Associations of clinical factors with case or control status were summarized as overall percentages and assessed using conditional logistic regression. Associations within cases were assessed using Fisher's exact test.
resultsReview of 361 charts identified 100 patients with IBD receiving narcotics (cases). One hundred matched controls were then identified. Cases were significantly associated with: female gender (64% cases versus 45% controls, P = 0.01), >or=2 IBD-related surgeries (42% versus 17%, P < 0.001), moderate-to-severe pain (93% versus 20%, P < 0.001), and moderate-to-severe symptoms (83% versus 33%, P < 0.001). Significant associations were detected for depression (42% versus 19%, P < 0.001), anxiety (19% versus 7%, P = 0.02), history of abuse (sexual, emotional, or physical, 17% versus 3%, P = 0.006), and for substance abuse (excluding alcohol) (14% versus 1%, P = 0.01). Of 39 cases that returned for follow-up, 22 (56%) had discontinued narcotics. Discontinuing narcotics was associated with medical treatment adherence (100% versus 53%), none-to-mild pain (73% versus 18%), and none-to-mild clinical activity (80% versus 24%).
conclusionsNarcotic use in IBD patients is associated with female gender, >or=2 previous surgeries, moderate to severe pain, and clinical disease activity, depression, anxiety, sexual, emotional and physical abuse, and substance abuse.
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19107782What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.