SynthesisHuman brain mapping2009
Functional brain imaging of swallowing: an activation likelihood estimation meta-analysis.
Synthesis in Human brain mapping, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 2 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Pooled it
- Basic taste processing recruits bilateral anteroventral and middle dorsal insulae: An activation likelihood estimation meta-analysis of fMRI studies.Brain and behavior · 2017Pooled it
- The effect and mechanism of motor imagery based on action observation treatment on dysphagia in Wallenberg Syndrome: a randomized controlled trial.European journal of physical and rehabilitation medicine · 2024Trial
- Exploring the Relationship Between Cerebral Blood Flow and Oral Exercise Using Head-Mounted Near-Infrared Spectroscopy.Dysphagia · 2026Article
- Article
- Cortical hemodynamic responses to acupuncture at Lianquan (CV23) in patients with post-stroke dysphagia: a functional near-infrared spectroscopy study.Frontiers in neurology · 2026Article
- Post-stroke dysphagia is associated with abnormal gamma power and phase synchronisation during swallowing.Frontiers in human neuroscience · 2026Article
- MRI-guided personalized tDCS planning for target engagement of the swallowing motor cortex after stroke: a finite-element modeling study.Frontiers in neurology · 2026Article
- Autonomic and neurosensory disorders in dementia with lewy bodies: prevalence and neural basis in the AlphaLewyMA cohort.Alzheimer's research & therapy · 2025Article
- White Matter Microstructural Correlates of Swallowing Biomechanics: An Exploratory Pilot Study in Healthy Young Adults.Dysphagia · 2025Article
- Morphological analysis and functional connectivity of the insular in patients with dysphagia after cerebral infarction based on resting-state fMRI.BMC neurology · 2025Article
- Review
- The Validation of the Italian Version of the Munich Swallowing Score (IT-MUCSS) Against the Fiberoptic Endoscopic Evaluation of Swallowing and Food Intake Modalities in Patients with Neurogenic Dysphagia: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Enhanced cortical activity of swallowing under acid stimulation in normal individuals: an fNIRS study.Frontiers in neurology · 2025Article
- Cortical activation characteristics during different swallowing tasks in post-stroke patients: a functional near-infrared spectroscopy study.Frontiers in neurology · 2025Article
- Expiratory Musculature Targeted Resistance Training Modulates Neural Connections During Swallowing Tasks: Preliminary fMRI Evidence.Neural plasticity · 2025Review
- Simultaneous Four Supratentorial Lesions Predict Tube Dependency Due to an Impaired Anticipatory Phase of Ingestion.Translational stroke research · 2024Article
- The potential positive effect of periodontal treatment on brain function activity using functional magnetic resonance imaging analysis.Journal of dental sciences · 2024Article
- Review
- Biomechanical and Cortical Control of Tongue Movements During Chewing and Swallowing.Dysphagia · 2024Review
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A quantitative, voxel-wise meta-analysis was performed to investigate the cortical control of water and saliva swallowing. Studies that were included in the meta-analysis (1) examined water swallowing, saliva swallowing, or both, and (2) reported brain activation as coordinates in standard space. Using these criteria, a systematic literature search identified seven studies that examined water swallowing and five studies of saliva swallowing. An activation likelihood estimation (ALE) meta-analysis of these studies was performed with GingerALE. For water swallowing, clusters with high activation likelihood were found in the bilateral sensorimotor cortex, right inferior parietal lobule, and right anterior insula. For saliva swallowing, clusters with high activation likelihood were found in the left sensorimotor cortex, right motor cortex, and bilateral cingulate gyrus. A between-condition meta-analysis revealed clusters with higher activation likelihood for water than for saliva swallowing in the right inferior parietal lobule, right postcentral gyrus, and right anterior insula. Clusters with higher activation likelihood for saliva than for water swallowing were found in the bilateral supplementary motor area, bilateral anterior cingulate gyrus, and bilateral precentral gyrus. This meta-analysis emphasizes the distributed and partly overlapping cortical networks involved in the control of water and saliva swallowing. Water swallowing is associated with right inferior parietal activation, likely reflecting the sensory processing of intraoral water stimulation. Saliva swallowing more strongly involves premotor areas, which are crucial for the initiation and control of movements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.