ArticleGenetica2009
Microsatellite mutation rates in the eastern tiger salamander (Ambystoma tigrinum tigrinum) differ 10-fold across loci.
Article in Genetica, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- A population genetic analysis of the Critically Endangered Madagascar big-headed turtle, Erymnochelys madagascariensis across captive and wild populations.Scientific reports · 2022Article
- Past and Recent Effects of Livestock Activity on the Genetic Diversity and Population Structure of Native Guanaco Populations of Arid Patagonia.Animals : an open access journal from MDPI · 2021Article
- Long-term urbanization impacts the eastern golden frog (Evolutionary applications · 2021Article
- Article
- Landscape genetics reveal broad and fine-scale population structure due to landscape features and climate history in the northern leopard frog (Ecology and evolution · 2019Article
- Long-term sky islands generate highly divergent lineages of a narrowly distributed stream salamander (Pachyhynobius shangchengensis) in mid-latitude mountains of East Asia.BMC evolutionary biology · 2019Article
- Phylogeography and Population Genetics ofFrontiers in genetics · 2019Article
- Testing models of refugial isolation, colonization and population connectivity in two species of montane salamanders.Heredity · 2017Article
- Article
- Islands within an island: Population genetic structure of the endemic Sardinian newt,Ecology and evolution · 2017Article
- Article
- A strong 'filter' effect of the East China Sea land bridge for East Asia's temperate plant species: inferences from molecular phylogeography and ecological niche modelling of Platycrater arguta (Hydrangeaceae).BMC evolutionary biology · 2014Article
- Genetic drift and rapid evolution of viviparity in insular fire salamanders (Salamandra salamandra).Heredity · 2012Article
- Demographic processes underlying subtle patterns of population structure in the scalloped hammerhead shark, Sphyrna lewini.PloS one · 2011Article
- Genetic diversity of Morato's Digger Toad, Proceratophrys moratoi: spatial structure, gene flow, effective size and the need for differential management strategies of populations.Genetics and molecular biologyArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microsatellites are commonly used for mapping and population genetics because of their high heterozygosities and allelic variability (i.e., polymorphism). Microsatellite markers are generally more polymorphic than other types of molecular markers such as allozymes or SNPs because the insertions/deletions that give rise to microsatellite variability are relatively common compared to nucleotide substitutions. Nevertheless, direct evidence of microsatellite mutation rates (MMRs) is lacking in most vertebrate groups despite the importance of such estimates to key population parameters (e.g., genetic differentiation or theta = 4N (e)micro). Herein, we present empirical data on MMRs in eastern tiger salamanders (Ambystoma tigrinum tigrinum). We conducted captive breeding trials and genotyped over 1,000 offspring at a suite of microsatellite loci. These data on 7,906 allele transfers provide the first direct estimates of MMRs in amphibians, and they illustrate that MMRs can vary by more than an order of magnitude across loci within a given species (one locus had ten mutations whereas the others had none).
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