ArticleLab on a chip2009
A microfluidic chip for real-time studies of the volume of single cells.
Article in Lab on a chip, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 52 citations in OpenAlex.
- A single-cell identification and capture chip for automatically and rapidly determining hydraulic permeability of cells.Analytical and bioanalytical chemistry · 2020Article
- Droplet-based microfluidic platform for measurement of rapid erythrocyte water transport.Lab on a chip · 2015Article
- Microfluidic impedance flow cytometry enabling high-throughput single-cell electrical property characterization.International journal of molecular sciences · 2015Review
- Review of methods to probe single cell metabolism and bioenergetics.Metabolic engineering · 2015Review
- Quantifying the volume of single cells continuously using a microfluidic pressure-driven trap with media exchange.Biomicrofluidics · 2014Article
- Microfluidic device for trapping and monitoring three dimensional multicell spheroids using electrical impedance spectroscopy.Biomicrofluidics · 2013Article
- Microfluidic impedance spectroscopy as a tool for quantitative biology and biotechnology.Biomicrofluidics · 2012Article
- Article
- A microfluidic device for simultaneous electrical and mechanical measurements on single cells.Biomicrofluidics · 2011Article
- Single-cell bioelectrical impedance platform for monitoring cellular response to drug treatment.Physical biology · 2011Article
- Measurement of the volume growth rate of single budding yeast with the MOSFET-based microfluidic Coulter counter.Lab on a chip · 2010Article
- An overview of recent strategies in pathogen sensing.Sensors (Basel, Switzerland) · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
We report a microfluidic chip that is capable of measuring volume changes in single cells in real-time. Single eukaryotic cells were immobilized in the sensing area and changes in volume in response to hypotonic challenges and drugs were measured using the electrical impedance method. Experiments on MDCK cells showed that the maximum swelling and the time course of swelling vary between individual cells following hypotonic stimulation. The microfluidic chip allows, rapid and convenient change of solutions, enabling detailed studies of various drugs and chemicals that may play important role in cell physiology at the single cell level.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.