ReviewPediatric nephrology (Berlin, Germany)2010
Diagnostic examination of the child with urolithiasis or nephrocalcinosis.
Review in Pediatric nephrology (Berlin, Germany), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it, 226 citations in OpenAlex.
- International Alliance of Urolithiasis (IAU) guidelines on the management of pediatric urolithiasis.Urolithiasis · 2024Guideline
- Urinary calcium and bone resorption markers during 3 years of denosumab treatment in pediatric osteogenesis imperfecta.JBMR plus · 2025Trial
- Marked increase in urinary excretion of apolipoproteins in children with nephrolithiasis associated with hypercalciuria.Pediatric nephrology (Berlin, Germany) · 2017Trial
- Spot Urine Calcium to Creatinine Ratio: Age-Specific Reference Ranges.Indian journal of pediatrics · 2026Article
- German Clinical Practice Guideline on Microhematuria in Children and Young Adults: Evaluating Early Detection of Kidney Disease.Kidney international reports · 2026Article
- Article
- Impact of different vitamin D supplementation doses on vitamin D status and bone metabolism in preterm infants.BMC pediatrics · 2026Article
- Urolithiasis in Children-Clinical Picture, Pathogenesis, and Diagnostic Approach.Biomolecules · 2026Review
- Etiology and longitudinal kidney outcomes in children with nephrocalcinosis: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Risk profile of promoters and inhibitors of kidney stone formation in paediatric inflammatory bowel disease.Pediatric nephrology (Berlin, Germany) · 2025Article
- Long-term kidney outcomes in patients with Kabuki syndrome.Pediatric nephrology (Berlin, Germany) · 2025Article
- Variable treatment response to lumasiran in pediatric patients with primary hyperoxaluria type 1.Pediatric nephrology (Berlin, Germany) · 2025Observational
- The global, regional, and national burden of pediatric stone disease: 1990-2021 and projections for the next two decades.Frontiers in pediatrics · 2025Article
- High altitude impact on serum bicarbonate in healthy Mexican children: concerning the overdiagnosis of renal tubular acidosis.BMC nephrology · 2024Article
- Risk factors for recurrence in pediatric urinary stone disease.Pediatric nephrology (Berlin, Germany) · 2024Article
- Renal calcification in children with renal tubular acidosis: What a paediatrician should know.World journal of clinical pediatrics · 2023Review
- Etiology and prognosis of nephrocalcinosis according to gestational age in Korean children.BMC pediatrics · 2023Article
- Urinary stone disease in Syrian children.Pediatric nephrology (Berlin, Germany) · 2023Article
- Is cerebral palsy associated with successful ureteral access during the initial attempt at ureteroscopy for urolithiasis in children and young adults?Journal of pediatric urology · 2023Article
- Secondary Prevention of Diabetes Type 1 with Oral Calcitriol and Analogs, the PRECAL Study.Children (Basel, Switzerland) · 2023Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urolithiasis and nephrocalcinosis are more frequent in children then currently anticipated, but still remain under- or misdiagnosed in a significant proportion of patients, since symptoms and signs may be subtle or misleading. All children with colicky abdominal pain or macroscopic hematuria should be examined thoroughly for urolithiasis. Also, other, more general, abdominal manifestations can be the first symptoms of renal stones. The patients and their family histories, as well as physical examination, are important initial steps for diagnostic evaluation. Thereafter, diagnostic imaging should be aimed at the location of calculi but also at identification of urinary tract anomalies or acute obstruction due to stone disease. This can often be accomplished by ultrasound examination alone, but sometimes radiological methods such as plain abdominal films or more sensitive non-enhanced computed tomography are necessary. Since metabolic causes are frequent in children, diagnostic evaluation should be meticulous so that metabolic disorders that cause recurrent urolithiasis or even renal failure, such as the primary hyperoxalurias and others, can be ruled out. The stone is not the disease itself; it is only one serious sign! Therefore, thorough and early diagnostic examination is mandatory for every infant and child with the first stone event, or with nephrocalcinosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.